{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mazurek A"],"funding":["John Paul II Hospital in Kraków Research Fund","Jagiellonian University Research"],"pagination":["4819"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9409706"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(16)"],"pubmed_abstract":["Background: Single-cohort studies suggest that second-generation stents (SGS; “mesh stents”) may improve carotid artery stenting (CAS) outcomes by limiting peri- and postprocedural cerebral embolism. SGS differ in the stent frame construction, mesh material, and design, as well as in mesh-to-frame position (inside/outside). Objectives: To compare clinical outcomes of SGS in relation to first-generation stents (FGSs; single-layer) in CAS. Methods: We performed a systematic review and meta-analysis of clinical studies with FGSs and SGS (PRISMA methodology, 3302 records). Endpoints were 30-day death, stroke, myocardial infarction (DSM), and 12-month ipsilateral stroke (IS) and restenosis (ISR). A random-effect model was applied. Results: Data of 68,422 patients from 112 eligible studies (68.2"],"journal":["Journal of clinical medicine"],"pubmed_title":["Clinical Outcomes of Second- versus First-Generation Carotid Stents: A Systematic Review and Meta-Analysis."],"pmcid":["PMC9409706"],"funding_grant_id":["K/ZDS/007819","N41/DBS/000822"],"pubmed_authors":["Amor M","Sirignano P","Pieniazek P","Schofer J","Musialek P","Schmidt A","Malinowski K","Karpenko A","Tekieli L","Speziale F","Setacci C","Stabile E","Siddiqui AH","Wissgott C","Capoccia L","Mazurek A","Micari A","Metzger DC","Kuczmik W","Cremonesi A","de Donato G","CARMEN (CArotid Revascularization Systematic Reviews and MEta-aNalyses) Investigators","Rosenfield K"],"additional_accession":[]},"is_claimable":false,"name":"Clinical Outcomes of Second- versus First-Generation Carotid Stents: A Systematic Review and Meta-Analysis.","description":"Background: Single-cohort studies suggest that second-generation stents (SGS; “mesh stents”) may improve carotid artery stenting (CAS) outcomes by limiting peri- and postprocedural cerebral embolism. SGS differ in the stent frame construction, mesh material, and design, as well as in mesh-to-frame position (inside/outside). Objectives: To compare clinical outcomes of SGS in relation to first-generation stents (FGSs; single-layer) in CAS. Methods: We performed a systematic review and meta-analysis of clinical studies with FGSs and SGS (PRISMA methodology, 3302 records). Endpoints were 30-day death, stroke, myocardial infarction (DSM), and 12-month ipsilateral stroke (IS) and restenosis (ISR). A random-effect model was applied. Results: Data of 68,422 patients from 112 eligible studies (68.2","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2026-06-21T03:17:22.65Z","creation":"2025-04-07T12:22:38.059Z"},"accession":"S-EPMC9409706","cross_references":{"pubmed":["36013058"],"doi":["10.3390/jcm11164819"]}}