biostudies-literatureWu WFMinistry of Science and Technology of Taiwan (MOST)Ditmanson Medical Foundation Chia-Yi Christian Hospital1276https://www.ebi.ac.uk/biostudies/studies/S-EPMC9409920biostudies-literatureUnknown12(8)<h4>Background</h4>While magnetic resonance imaging (MRI) is the imaging modality of choice for the evaluation of patients with brain tumors, it may still be challenging to differentiate glioblastoma multiforme (GBM) from solitary brain metastasis (SBM) due to their similar imaging features. This study aimed to evaluate the features extracted of dual-tree complex wavelet transform (DTCWT) from routine MRI protocol for preoperative differentiation of glioblastoma (GBM) and solitary brain metastasis (SBM).<h4>Methods</h4>A total of 51 patients were recruited, including 27 GBM and 24 SBM patients. Their contrast-enhanced T1-weighted images (CET1WIs), T2 fluid-attenuated inversion recovery (T2FLAIR) images, diffusion-weighted images (DWIs), and apparent diffusion coefficient (ADC) images were Journal of personalized medicineThe Application of DTCWT on MRI-Derived Radiomics for Differentiation of Glioblastoma and Solitary Brain Metastases.PMC9409920109-2113-M-194-010-MY3R110-039Lin ECShen CWChen YJLai KMChen CCWu WFfalseThe Application of DTCWT on MRI-Derived Radiomics for Differentiation of Glioblastoma and Solitary Brain Metastases.<h4>Background</h4>While magnetic resonance imaging (MRI) is the imaging modality of choice for the evaluation of patients with brain tumors, it may still be challenging to differentiate glioblastoma multiforme (GBM) from solitary brain metastasis (SBM) due to their similar imaging features. This study aimed to evaluate the features extracted of dual-tree complex wavelet transform (DTCWT) from routine MRI protocol for preoperative differentiation of glioblastoma (GBM) and solitary brain metastasis (SBM).<h4>Methods</h4>A total of 51 patients were recruited, including 27 GBM and 24 SBM patients. Their contrast-enhanced T1-weighted images (CET1WIs), T2 fluid-attenuated inversion recovery (T2FLAIR) images, diffusion-weighted images (DWIs), and apparent diffusion coefficient (ADC) images were 2022-01-01T00:00:00Z2022 Aug2025-05-29T19:22:28.65Z2025-05-29T19:22:28.65ZS-EPMC94099203601322510.3390/jpm12081276