{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Rojas-Rechy MH"],"funding":["Fondo de Apoyo a la Investigación, Hospital Infantil de México Federico Gómez"],"pagination":["1685"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9414306"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(8)"],"pubmed_abstract":["Infections remain a major cause of morbidity and mortality among hematopoietic stem cell transplant (HSCT) recipients. Unlike Epstein-Barr Virus (EBV) and Human Cytomegalovirus (HCMV), Human Herpesvirus (HHV) 6, HHV7 and HHV8 are not routinely monitored in many centers, especially in the pediatric population of low-medium income countries. We screened EBV, HCMV, HHV6, HHV7 and HHV8 in 412 leukocytes-plasma paired samples from 40 pediatric patients assisted in a tertiary hospital in Mexico. Thirty-two underwent allo-HSCT, whereas eight received auto-HSCT. Overall viral detection frequencies in allo- and auto-HSCT were: EBV = 43.7% and 30.0%, HCMV = 5.0% and 6.7%, HHV6 = 7.9% and 20.0% and HHV7 = 9.7% and 23.3%. HHV8 was not detected in any sample. Interestingly, HHV6 and HHV7 were more freq"],"journal":["Microorganisms"],"pubmed_title":["Herpesvirus Screening in Childhood Hematopoietic Transplant Reveals High Systemic Inflammation in Episodes of Multiple Viral Detection and an EBV Association with Elevated IL-1β, IL-8 and Graft-Versus-Host Disease."],"pmcid":["PMC9414306"],"funding_grant_id":["CONACyT FOSISS-2015-2-261307","HIM/2016/089 SSA 1288","HIM/2017/145 SSA 1469","HIM/2016/021 SSA 1237","HIM/2016/089","HIM/2017/145"],"pubmed_authors":["Lopez-Martinez B","Rojas-Rechy MH","Martinez-Ruiz GU","Morales-Sanchez A","Fuentes-Panana EM","Gaytan-Morales F","Castorena-Villa I","Parra-Ortega I","Escamilla-Nunez MC","Pompa-Mera EN","Sanchez-Ponce Y","Mendez-Tenorio A"],"additional_accession":[]},"is_claimable":false,"name":"Herpesvirus Screening in Childhood Hematopoietic Transplant Reveals High Systemic Inflammation in Episodes of Multiple Viral Detection and an EBV Association with Elevated IL-1β, IL-8 and Graft-Versus-Host Disease.","description":"Infections remain a major cause of morbidity and mortality among hematopoietic stem cell transplant (HSCT) recipients. Unlike Epstein-Barr Virus (EBV) and Human Cytomegalovirus (HCMV), Human Herpesvirus (HHV) 6, HHV7 and HHV8 are not routinely monitored in many centers, especially in the pediatric population of low-medium income countries. We screened EBV, HCMV, HHV6, HHV7 and HHV8 in 412 leukocytes-plasma paired samples from 40 pediatric patients assisted in a tertiary hospital in Mexico. Thirty-two underwent allo-HSCT, whereas eight received auto-HSCT. Overall viral detection frequencies in allo- and auto-HSCT were: EBV = 43.7% and 30.0%, HCMV = 5.0% and 6.7%, HHV6 = 7.9% and 20.0% and HHV7 = 9.7% and 23.3%. HHV8 was not detected in any sample. Interestingly, HHV6 and HHV7 were more freq","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2026-05-08T03:07:13.006Z","creation":"2024-11-06T07:17:13.403Z"},"accession":"S-EPMC9414306","cross_references":{"pubmed":["36014102"],"doi":["10.3390/microorganisms10081685"]}}