{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Nakano K"],"funding":["Ministry of Education, Culture, Sports, Science and Technology"],"pagination":["5103"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9415352"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["27(16)"],"pubmed_abstract":["Spiro-fused polycyclic aromatic compounds (PACs) have received growing interest as rigid chiral scaffolds. However, furan-containing spiro-fused PACs have been quite limited. Here, we design spiro[indeno[1,2-<i>b</i>][1]benzofuran-10,10'-indeno[1,2-<i>b</i>][1]benzothiophene] as a new family of spiro-fused PACs that contains a furan unit. The compound was successfully synthesized in enantiopure form and also transformed to its <i>S</i>,<i>S</i>-dioxide derivative and the pyrrole-containing analog via aromatic metamorphosis. The absorption and emission properties of the obtained furan-containing chiral spiro-fused PACs are apparently different from those of their thiophene analogs that have been reported, owing to the increased electron-richness of furan compared to thiophene. All of the fu"],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["Furan-Containing Chiral Spiro-Fused Polycyclic Aromatic Compounds: Synthesis and Photophysical Properties."],"pmcid":["PMC9415352"],"funding_grant_id":["16H00824"],"pubmed_authors":["Takase K","Noguchi K","Nakano K"],"additional_accession":[]},"is_claimable":false,"name":"Furan-Containing Chiral Spiro-Fused Polycyclic Aromatic Compounds: Synthesis and Photophysical Properties.","description":"Spiro-fused polycyclic aromatic compounds (PACs) have received growing interest as rigid chiral scaffolds. However, furan-containing spiro-fused PACs have been quite limited. Here, we design spiro[indeno[1,2-<i>b</i>][1]benzofuran-10,10'-indeno[1,2-<i>b</i>][1]benzothiophene] as a new family of spiro-fused PACs that contains a furan unit. The compound was successfully synthesized in enantiopure form and also transformed to its <i>S</i>,<i>S</i>-dioxide derivative and the pyrrole-containing analog via aromatic metamorphosis. The absorption and emission properties of the obtained furan-containing chiral spiro-fused PACs are apparently different from those of their thiophene analogs that have been reported, owing to the increased electron-richness of furan compared to thiophene. All of the fu","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-18T22:51:09.34Z","creation":"2025-04-07T10:33:24.452Z"},"accession":"S-EPMC9415352","cross_references":{"pubmed":["36014343"],"doi":["10.3390/molecules27165103"]}}