{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Leibman-Markus M"],"funding":["Israel Academy of Sciences and Humanities","Maïmonide-Israel","Conicyt"],"pagination":["760"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9415932"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(8)"],"pubmed_abstract":["Pattern recognition receptor (PRR) trafficking to the plasma membrane and endocytosis plays a crucial role in pattern triggered immunity (PTI). Dynamin-related proteins (DRPs) participate in endocytosis and recycling. In Arabidopsis, DRP1 and DRP2 are involved in plasma membrane scission during endocytosis. They are required for the PRR FLS2 endocytosis induction and PTI activation after elicitation with flg22, the MAMP recognized by FLS2. In tomato, SlDRP2A regulates the PRR LeEIX2 endocytosis and PTI activation in response to EIX, the MAMP recognized by LeEIX2. However, it is unknown if other DRPs participate in these processes. Taking advantage of bioinformatics tools, we selected SlDRP2B among the eight DRP2 tomato orthologues to study its functionality in trafficking and plant immunit"],"journal":["Membranes"],"pubmed_title":["Dynamin-Related Proteins Enhance Tomato Immunity by Mediating Pattern Recognition Receptor Trafficking."],"pmcid":["PMC9415932"],"funding_grant_id":["2018","550/18","PAI 77190027"],"pubmed_authors":["Vasquez-Soto B","Pizarro L","Leibman-Markus M","Schuster S","Avni A","Bar M"],"additional_accession":[]},"is_claimable":false,"name":"Dynamin-Related Proteins Enhance Tomato Immunity by Mediating Pattern Recognition Receptor Trafficking.","description":"Pattern recognition receptor (PRR) trafficking to the plasma membrane and endocytosis plays a crucial role in pattern triggered immunity (PTI). Dynamin-related proteins (DRPs) participate in endocytosis and recycling. In Arabidopsis, DRP1 and DRP2 are involved in plasma membrane scission during endocytosis. They are required for the PRR FLS2 endocytosis induction and PTI activation after elicitation with flg22, the MAMP recognized by FLS2. In tomato, SlDRP2A regulates the PRR LeEIX2 endocytosis and PTI activation in response to EIX, the MAMP recognized by LeEIX2. However, it is unknown if other DRPs participate in these processes. Taking advantage of bioinformatics tools, we selected SlDRP2B among the eight DRP2 tomato orthologues to study its functionality in trafficking and plant immunit","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-18T15:48:46.005Z","creation":"2025-04-07T02:40:23.606Z"},"accession":"S-EPMC9415932","cross_references":{"pubmed":["36005675"],"doi":["10.3390/membranes12080760"]}}