{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["6(8)"],"submitter":["Gurevitz C"],"pubmed_abstract":["<h4>Background</h4>Actinomycosis is a chronic invasive infection caused by <i>Actinomyces</i> species. Actinomycosis endocarditis has been described, yet considered rare. We present the first reported transcatheter aortic valve implantation (TAVI)-related actinomycosis endocarditis.<h4>Case summary</h4>A 70-year-old female patient, presented 4 months after TAVI with malaise and vocal-cord paralysis. She underwent computed tomography angiography which demonstrated a 28 mm pseudoaneurysm of the ascending aorta, which compressed the laryngeal nerves. Her condition rapidly deteriorated with cardiogenic shock and required an emergent surgery, which reviled a tamponade with active bleeding, due to an ascending aortic dissection. She underwent aortic valve and ascending aorta replacement. A 2 cm vegetation was found on the TAVI prosthetic valve and sent for cultures, which later revealed an <i>Actinomyces neuii</i> infection. Long-term intravenous ampicillin treatment was given.<h4>Discussion</h4>This case describes a patient with endocarditis on TAVI prosthetic valve, with an unusual clinical presentation and rapid deterioration to an emergency intervention. This unique presentation of tumour-like tissue invasion is characteristic of actinomycosis, and should be suspected especially following valve replacement."],"journal":["European heart journal. Case reports"],"pagination":["ytac302"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9420195"],"repository":["biostudies-literature"],"pubmed_title":["An unusual case report of transcatheter aortic valve implantation-related actinomycosis endocarditis."],"pmcid":["PMC9420195"],"pubmed_authors":["Rubchevsky V","Gurevitz C","Orvin K","Hamdan A"],"additional_accession":[]},"is_claimable":false,"name":"An unusual case report of transcatheter aortic valve implantation-related actinomycosis endocarditis.","description":"<h4>Background</h4>Actinomycosis is a chronic invasive infection caused by <i>Actinomyces</i> species. Actinomycosis endocarditis has been described, yet considered rare. We present the first reported transcatheter aortic valve implantation (TAVI)-related actinomycosis endocarditis.<h4>Case summary</h4>A 70-year-old female patient, presented 4 months after TAVI with malaise and vocal-cord paralysis. She underwent computed tomography angiography which demonstrated a 28 mm pseudoaneurysm of the ascending aorta, which compressed the laryngeal nerves. Her condition rapidly deteriorated with cardiogenic shock and required an emergent surgery, which reviled a tamponade with active bleeding, due to an ascending aortic dissection. She underwent aortic valve and ascending aorta replacement. A 2 cm vegetation was found on the TAVI prosthetic valve and sent for cultures, which later revealed an <i>Actinomyces neuii</i> infection. Long-term intravenous ampicillin treatment was given.<h4>Discussion</h4>This case describes a patient with endocarditis on TAVI prosthetic valve, with an unusual clinical presentation and rapid deterioration to an emergency intervention. This unique presentation of tumour-like tissue invasion is characteristic of actinomycosis, and should be suspected especially following valve replacement.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-08-30T03:15:09.591Z","creation":"2025-04-07T06:48:57.831Z"},"accession":"S-EPMC9420195","cross_references":{"pubmed":["36043211"],"doi":["10.1093/ehjcr/ytac302"]}}