biostudies-literatureUnknown2022Sharma MKTuberculosis is a significant cause of morbidity worldwide and is a priority at the provincial and federal levels in Canada. It is known that tuberculosis transmission networks are complex and span many years as well as different jurisdictions and countries. MIRU-VNTR is a universal tuberculosis genotyping method that utilizes a 24-loci pattern and it has shown promise in identifying inter and intrajurisdictional clusters within Canada. MIRU-VNTR data collected over 10 years from the National Reference Centre for Mycobacteriology (NRCM) were analyzed in this study. Some clusters were unique to a single province/territory, while others spanned multiple provinces and/or territories in Canada. The use of a universal laboratory test can enhance contact tracing, provide geographical informationThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale3505142https://www.ebi.ac.uk/biostudies/studies/S-EPMC9424012biostudies-literatureCompilation of 10 Years of MIRU-VNTR Data: Canadian National Tuberculosis Laboratory's Experience.PMC9424012McGurran AMacKenzie HHaldane DAdam HSoualhine HJanella DTyrrell GMinion JSekirov IAkochy PMNewberry CPatterson MCorbett CSharma MKNeedle RfalseCompilation of 10 Years of MIRU-VNTR Data: Canadian National Tuberculosis Laboratory's Experience.Tuberculosis is a significant cause of morbidity worldwide and is a priority at the provincial and federal levels in Canada. It is known that tuberculosis transmission networks are complex and span many years as well as different jurisdictions and countries. MIRU-VNTR is a universal tuberculosis genotyping method that utilizes a 24-loci pattern and it has shown promise in identifying inter and intrajurisdictional clusters within Canada. MIRU-VNTR data collected over 10 years from the National Reference Centre for Mycobacteriology (NRCM) were analyzed in this study. Some clusters were unique to a single province/territory, while others spanned multiple provinces and/or territories in Canada. The use of a universal laboratory test can enhance contact tracing, provide geographical information2022-01-01T00:00:00Z20222025-04-22T03:37:14.567Z2025-04-05T20:44:36.888ZS-EPMC94240123604617410.1155/2022/3505142