{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Cea-Sanchez S"],"funding":["Ministry of Science and Innovation, Spain.","NIGMS NIH HHS"],"pagination":["e0150522"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9426599"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(4)"],"pubmed_abstract":["Asexual reproduction in fungi facilitates the dispersal and colonization of new substrates and, in pathogenic fungi, allows infection of plants and animals. The velvet complex is a fungus-specific protein complex that participates in the regulation of gene expression in response to environmental signals like light, as well as developmental processes, pathogenesis, and secondary metabolism. The velvet complex in the fungus Neurospora crassa is composed of three proteins, VE-1, VE-2, and LAE-1. Mutations in <i>ve-1</i> or <i>ve-2</i>, but not in <i>lae-1</i>, led to shorter heights of aerial tissue, a mixture of aerial hyphae and developing macroconidia, and increased microconidiation when they were combined with mutations in the transcription factor gene <i>fl</i>. VE-2 and LAE-1 were detec"],"journal":["mBio"],"pubmed_title":["Transcriptional Regulation by the Velvet Protein VE-1 during Asexual Development in the Fungus Neurospora crassa."],"pmcid":["PMC9426599"],"funding_grant_id":["P01 GM068087","RTI2018-098636-B-I00"],"pubmed_authors":["Glass NL","Canovas D","Cea-Sanchez S","Corrochano-Luque M","Corrochano LM","Gutierrez G"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptional Regulation by the Velvet Protein VE-1 during Asexual Development in the Fungus Neurospora crassa.","description":"Asexual reproduction in fungi facilitates the dispersal and colonization of new substrates and, in pathogenic fungi, allows infection of plants and animals. The velvet complex is a fungus-specific protein complex that participates in the regulation of gene expression in response to environmental signals like light, as well as developmental processes, pathogenesis, and secondary metabolism. The velvet complex in the fungus Neurospora crassa is composed of three proteins, VE-1, VE-2, and LAE-1. Mutations in <i>ve-1</i> or <i>ve-2</i>, but not in <i>lae-1</i>, led to shorter heights of aerial tissue, a mixture of aerial hyphae and developing macroconidia, and increased microconidiation when they were combined with mutations in the transcription factor gene <i>fl</i>. VE-2 and LAE-1 were detec","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2026-06-13T06:03:41.581Z","creation":"2025-02-19T03:28:48.662Z"},"accession":"S-EPMC9426599","cross_references":{"pubmed":["35913159"],"doi":["10.1128/mbio.01505-22"]}}