biostudies-literatureUnknown9Xu J<h4>Background</h4>Elevated level of low-density lipoprotein cholesterol (LDL-C) is concerned as one of the main risk factors for cardiovascular disease, in both the fasting and postprandial states. This study aimed to compare the measured LDL-C with LDL-C calculated by the Friedewald, Martin-Hopkins, Vujovic, and Sampson formulas, and establish which formula could provide the most reliable LDL-C results for Chinese subjects, especially at the postprandial state.<h4>Methods</h4>Twenty-six subjects were enrolled in this study. The blood samples were collected from all the subjects before and after taking a daily breakfast. The calculated LDL-C results were compared with LDL-C measured by the vertical auto profile method, at both the fasting and postprandial states. The percentage differenceFrontiers in cardiovascular medicine944003https://www.ebi.ac.uk/biostudies/studies/S-EPMC9433804biostudies-literatureThe accuracy of four formulas for LDL-C calculation at the fasting and postprandial states.PMC9433804Xiang QLiu LZhu LDu XZhang SXu JfalseThe accuracy of four formulas for LDL-C calculation at the fasting and postprandial states.<h4>Background</h4>Elevated level of low-density lipoprotein cholesterol (LDL-C) is concerned as one of the main risk factors for cardiovascular disease, in both the fasting and postprandial states. This study aimed to compare the measured LDL-C with LDL-C calculated by the Friedewald, Martin-Hopkins, Vujovic, and Sampson formulas, and establish which formula could provide the most reliable LDL-C results for Chinese subjects, especially at the postprandial state.<h4>Methods</h4>Twenty-six subjects were enrolled in this study. The blood samples were collected from all the subjects before and after taking a daily breakfast. The calculated LDL-C results were compared with LDL-C measured by the vertical auto profile method, at both the fasting and postprandial states. The percentage difference2022-01-01T00:00:00Z20222025-04-25T19:11:09.918Z2025-04-06T07:49:58.591ZS-EPMC94338043606156910.3389/fcvm.2022.944003