{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13(17)"],"submitter":["Cai JS"],"pubmed_abstract":["<h4>Background</h4>Lymphovascular invasion (LVI) has not been included in the tumor-node-metastasis (TNM) staging manual of non-small-cell lung cancer (NSCLC). We aimed to investigate the predictive value of LVI on stage IA NSCLC and proposed a method of incorporating LVI into the T category based on the latest TNM staging manual.<h4>Methods</h4>The least absolute shrinkage and selection operator (LASSO)-penalized Cox multivariable regression model was performed to identify prognostic factors. The Kaplan-Meier method was used to compare overall survival (OS) and disease-free survival (DFS) between groups. Propensity score matching (PSM) was used to minimize bias.<h4>Results</h4>A total of 1452 eligible stage I NSCLC cases (stage IA without LVI, 1022 cases; stage IA with LVI, 120 cases; sta"],"journal":["Thoracic cancer"],"pagination":["2413-2420"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9436680"],"repository":["biostudies-literature"],"pubmed_title":["Lymphovascular invasion: A non-sized T descriptor for stage IA non-small cell lung cancer."],"pmcid":["PMC9436680"],"pubmed_authors":["Li Y","Cai JS","Wang X","Yang F","Qiu MT"],"additional_accession":[]},"is_claimable":false,"name":"Lymphovascular invasion: A non-sized T descriptor for stage IA non-small cell lung cancer.","description":"<h4>Background</h4>Lymphovascular invasion (LVI) has not been included in the tumor-node-metastasis (TNM) staging manual of non-small-cell lung cancer (NSCLC). We aimed to investigate the predictive value of LVI on stage IA NSCLC and proposed a method of incorporating LVI into the T category based on the latest TNM staging manual.<h4>Methods</h4>The least absolute shrinkage and selection operator (LASSO)-penalized Cox multivariable regression model was performed to identify prognostic factors. The Kaplan-Meier method was used to compare overall survival (OS) and disease-free survival (DFS) between groups. Propensity score matching (PSM) was used to minimize bias.<h4>Results</h4>A total of 1452 eligible stage I NSCLC cases (stage IA without LVI, 1022 cases; stage IA with LVI, 120 cases; sta","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-05T10:25:59.988Z","creation":"2025-04-05T10:25:59.988Z"},"accession":"S-EPMC9436680","cross_references":{"pubmed":["35670186"],"doi":["10.1111/1759-7714.14530"]}}