biostudies-literatureTrefzer TBGerman Center for Lung Research3116-3129https://www.ebi.ac.uk/biostudies/studies/S-EPMC9437562biostudies-literatureUnknown82(17)<h4>Significance</h4>Single-cell analysis of healthy lung tissue and lung cancer reveals distinct tumor cell populations, including cells with differential immune modulating capacity between smokers and never smokers, which could guide future therapeutic strategies.Cancer researchIntratumoral Heterogeneity and Immune Modulation in Lung Adenocarcinoma in Female Smokers and Never Smokers.PMC943756282DZL00402Trefzer TBKriegsmann MMuley TMeister MEils RWinter HSchneider MAJechow KConrad CChua RLfalseIntratumoral Heterogeneity and Immune Modulation in Lung Adenocarcinoma in Female Smokers and Never Smokers.<h4>Significance</h4>Single-cell analysis of healthy lung tissue and lung cancer reveals distinct tumor cell populations, including cells with differential immune modulating capacity between smokers and never smokers, which could guide future therapeutic strategies.2022-01-01T00:00:00Z2022 Sep2026-05-28T03:42:55.424Z2025-04-04T20:22:17.723ZS-EPMC94375623581925210.1158/0008-5472.CAN-21-3836