{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(8)"],"submitter":["Zhang Y"],"pubmed_abstract":["<h4>Introduction</h4>Sedation and analgesia are recommended to be employed in the intensive care unit (ICU) to enhance patient comfort and safety, facilitate mechanical ventilation and reduce oxygen demands. However, the increasing evidence demonstrates that excessive sedation and analgesia might prolong mechanical ventilation and increase costs and mortality. Acupuncture is known to be able to attenuate pain, anxiety and agitation symptoms while avoiding excessive sedation and analgesia caused by drugs. Therefore, we present a protocol to investigate whether acupuncture, used for sedation and analgesia, can reduce the duration of mechanical ventilation, save medical resources and reduce the mortality of critically ill patients receiving mechanical ventilation.<h4>Methods and analysis</h4>"],"journal":["BMJ open"],"pagination":["e059741"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9438044"],"repository":["biostudies-literature"],"pubmed_title":["Prospective comparison of acupuncture with sham acupuncture to determine impact on sedation and analgesia in mechanically ventilated critically ill patients (PASSION study): protocol for a randomised controlled trial."],"pmcid":["PMC9438044"],"pubmed_authors":["Yang G","Zhang MZ","Mao S","Zhang Y","Chen F","Wei J"],"additional_accession":[]},"is_claimable":false,"name":"Prospective comparison of acupuncture with sham acupuncture to determine impact on sedation and analgesia in mechanically ventilated critically ill patients (PASSION study): protocol for a randomised controlled trial.","description":"<h4>Introduction</h4>Sedation and analgesia are recommended to be employed in the intensive care unit (ICU) to enhance patient comfort and safety, facilitate mechanical ventilation and reduce oxygen demands. However, the increasing evidence demonstrates that excessive sedation and analgesia might prolong mechanical ventilation and increase costs and mortality. Acupuncture is known to be able to attenuate pain, anxiety and agitation symptoms while avoiding excessive sedation and analgesia caused by drugs. Therefore, we present a protocol to investigate whether acupuncture, used for sedation and analgesia, can reduce the duration of mechanical ventilation, save medical resources and reduce the mortality of critically ill patients receiving mechanical ventilation.<h4>Methods and analysis</h4>","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-04T21:52:06.475Z","creation":"2025-04-04T21:52:06.475Z"},"accession":"S-EPMC9438044","cross_references":{"pubmed":["36041767"],"doi":["10.1136/bmjopen-2021-059741"]}}