{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Khurshid S"],"funding":["U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI)","American Heart Association (American Heart Association, Inc.)"],"pagination":["131"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9440134"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["5(1)"],"pubmed_abstract":["Physical activity is regarded as favorable to health but effects across the spectrum of human disease are poorly quantified. In contrast to self-reported measures, wearable accelerometers can provide more precise and reproducible activity quantification. Using wrist-worn accelerometry data from the UK Biobank prospective cohort study, we test associations between moderate-to-vigorous physical activity (MVPA) - both total MVPA minutes and whether MVPA is above a guideline-based threshold of ≥150 min/week-and incidence of 697 diseases using Cox proportional hazards models adjusted for age, sex, body mass index, smoking, Townsend Deprivation Index, educational attainment, diet quality, alcohol use, blood pressure, anti-hypertensive use. We correct for multiplicity at a false discovery rate of"],"journal":["NPJ digital medicine"],"pubmed_title":["Wearable accelerometer-derived physical activity and incident disease."],"pmcid":["PMC9440134"],"funding_grant_id":["R01HL139731","R01HL141434","R01HL092577","K24HL105780","18SFRN34250007","T32HL007604","18SFRN34110082","1RO1HL092577","1R01AG066914","R01AG066010","2U54HL120163"],"pubmed_authors":["Pirruccello JP","Venn RA","Khurshid S","Weng LC","Ellinor PT","Al-Alusi MA","Lubitz SA","Nauffal V","Benjamin EJ"],"additional_accession":[]},"is_claimable":false,"name":"Wearable accelerometer-derived physical activity and incident disease.","description":"Physical activity is regarded as favorable to health but effects across the spectrum of human disease are poorly quantified. In contrast to self-reported measures, wearable accelerometers can provide more precise and reproducible activity quantification. Using wrist-worn accelerometry data from the UK Biobank prospective cohort study, we test associations between moderate-to-vigorous physical activity (MVPA) - both total MVPA minutes and whether MVPA is above a guideline-based threshold of ≥150 min/week-and incidence of 697 diseases using Cox proportional hazards models adjusted for age, sex, body mass index, smoking, Townsend Deprivation Index, educational attainment, diet quality, alcohol use, blood pressure, anti-hypertensive use. We correct for multiplicity at a false discovery rate of","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-18T20:53:37.899Z","creation":"2025-04-07T08:58:32.315Z"},"accession":"S-EPMC9440134","cross_references":{"pubmed":["36056190"],"doi":["10.1038/s41746-022-00676-9"]}}