biostudies-literatureUnknown17(1)Panagidi M<h4>Objectives</h4>Phase angle (PA) constitutes a bioelectrical impedance measurement, indicating cell membrane health and integrity, hydration, and nutritional status. Handgrip strength (HS) has been also associated with body composition, nutritional status, inflammation, and functional ability in several chronic diseases. Although their prognostic significance as independent biomarkers has been already investigated regarding the outcomes of a cardiac surgery, our study is the first one to assess the combined predictive value of preoperative PA and HS.<h4>Design and methods</h4>HS and PA measurements were performed preoperativelyin 195 patients undergoing cardiac surgery. The association ofthe combination of HS and PAwith all-cause mortality rates was the primary study outcome, while its Journal of cardiothoracic surgery227https://www.ebi.ac.uk/biostudies/studies/S-EPMC9440499biostudies-literaturePrognostic value of combined preoperative phase angle and handgrip strength in cardiac surgery.PMC9440499Panagidi MMoysidis DVPapazoglou ΑSGalanos AAnastasiadis KPapadakis MKouidi ETagarakis GVlachopoulou EfalsePrognostic value of combined preoperative phase angle and handgrip strength in cardiac surgery.<h4>Objectives</h4>Phase angle (PA) constitutes a bioelectrical impedance measurement, indicating cell membrane health and integrity, hydration, and nutritional status. Handgrip strength (HS) has been also associated with body composition, nutritional status, inflammation, and functional ability in several chronic diseases. Although their prognostic significance as independent biomarkers has been already investigated regarding the outcomes of a cardiac surgery, our study is the first one to assess the combined predictive value of preoperative PA and HS.<h4>Design and methods</h4>HS and PA measurements were performed preoperativelyin 195 patients undergoing cardiac surgery. The association ofthe combination of HS and PAwith all-cause mortality rates was the primary study outcome, while its 2022-01-01T00:00:00Z2022 Sep2025-04-19T06:19:10.488Z2025-04-19T06:19:10.488ZS-EPMC94404993605761910.1186/s13019-022-01970-z