{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["69(3)"],"submitter":["Nguyen M"],"pubmed_abstract":["<h4>Introduction</h4>Paediatric patients (individuals below 18 years of age) requiring cranial-spinal irradiation (CSI) at our institution are commonly planned and treated using a three isocentre (3-ISO) volumetric modulated arc therapy (VMAT) technique. A modified two isocentre (2-ISO) VMAT technique was investigated with the aim to improve workflow and reduce planning and treatment time.<h4>Methods</h4>Five CSI paediatric patients previously treated with a 3-ISO VMAT technique were retrospectively replanned using a 2-ISO VMAT technique. The 2-ISO VMAT plans were reviewed and approved by a radiation oncologist (RO) before undergoing patient-specific quality assurance (QA) procedures, performed by a radiation oncology medical physicist (ROMP). Planning target volume (PTV) coverage, organ-a"],"journal":["Journal of medical radiation sciences"],"pagination":["357-366"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9442318"],"repository":["biostudies-literature"],"pubmed_title":["Modified volumetric modulated arc therapy technique with reduced planning and treatment time for craniospinal irradiation utilising two isocentres."],"pmcid":["PMC9442318"],"pubmed_authors":["Sim L","Pullar A","Cheuk R","Gibbs A","Dang T","Deegan L","Hargrave C","Nguyen M","Henry K","Jones S"],"additional_accession":[]},"is_claimable":false,"name":"Modified volumetric modulated arc therapy technique with reduced planning and treatment time for craniospinal irradiation utilising two isocentres.","description":"<h4>Introduction</h4>Paediatric patients (individuals below 18 years of age) requiring cranial-spinal irradiation (CSI) at our institution are commonly planned and treated using a three isocentre (3-ISO) volumetric modulated arc therapy (VMAT) technique. A modified two isocentre (2-ISO) VMAT technique was investigated with the aim to improve workflow and reduce planning and treatment time.<h4>Methods</h4>Five CSI paediatric patients previously treated with a 3-ISO VMAT technique were retrospectively replanned using a 2-ISO VMAT technique. The 2-ISO VMAT plans were reviewed and approved by a radiation oncologist (RO) before undergoing patient-specific quality assurance (QA) procedures, performed by a radiation oncology medical physicist (ROMP). Planning target volume (PTV) coverage, organ-a","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-20T00:39:25.462Z","creation":"2025-04-20T00:39:25.462Z"},"accession":"S-EPMC9442318","cross_references":{"pubmed":["35460199"],"doi":["10.1002/jmrs.582"]}}