{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Wang H"],"pubmed_abstract":["<h4>Background</h4>Acute kidney injury (AKI) is a common postoperative complication in pediatric patients undergoing cardiac surgery and associated with poor outcomes. Dexmedetomidine has the pharmacological features of organ protection in cardiac surgery patients. The aim of this meta-analysis is to investigate the effect of dexmedetomidine infusion on the incidence of AKI after cardiac surgery in pediatric patients.<h4>Methods</h4>The databases of Pubmed, Embase, and Cochrane Library were searched until April 24, 2022 following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. RevMan 5.3 was used to perform statistical analyses.<h4>Results</h4>Five relevant trials with a total of 630 patients were included. The pooled result using fixed-effects m"],"journal":["Frontiers in cardiovascular medicine"],"pagination":["938790"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9448974"],"repository":["biostudies-literature"],"pubmed_title":["Dexmedetomidine and acute kidney injury following cardiac surgery in pediatric patients-An updated systematic review and meta-analysis."],"pmcid":["PMC9448974"],"pubmed_authors":["Yuan S","Li Y","Jia Y","Wang H","Zhang C","Wang J","Yan F"],"additional_accession":[]},"is_claimable":false,"name":"Dexmedetomidine and acute kidney injury following cardiac surgery in pediatric patients-An updated systematic review and meta-analysis.","description":"<h4>Background</h4>Acute kidney injury (AKI) is a common postoperative complication in pediatric patients undergoing cardiac surgery and associated with poor outcomes. Dexmedetomidine has the pharmacological features of organ protection in cardiac surgery patients. The aim of this meta-analysis is to investigate the effect of dexmedetomidine infusion on the incidence of AKI after cardiac surgery in pediatric patients.<h4>Methods</h4>The databases of Pubmed, Embase, and Cochrane Library were searched until April 24, 2022 following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. RevMan 5.3 was used to perform statistical analyses.<h4>Results</h4>Five relevant trials with a total of 630 patients were included. The pooled result using fixed-effects m","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T07:15:36.561Z","creation":"2025-04-04T07:15:36.561Z"},"accession":"S-EPMC9448974","cross_references":{"pubmed":["36093139"],"doi":["10.3389/fcvm.2022.938790"]}}