{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Liu X"],"pubmed_abstract":["<h4>Background</h4>Obstructive sleep apnea (OSA) is associated with cerebral small vessel disease (CSVD). Nonetheless, whether OSA-risk determined by a simple screening questionnaire or indices quantifying nocturnal hypoxemia other than the conventional apnea-hypopnea index (AHI) by the home sleep apnea test (HSAT) associated with CSVD burden remains uncertain.<h4>Methods</h4>From 2018 to 2021, we recruited patients with transient ischemic attack (TIA)/minor stroke from the Queen Mary Hospital Acute Stroke Unit and TIA/Stroke Outpatient Clinics. Logistic regression models were applied to determine the association of baseline OSA-risk (on STOP-BANG questionnaire) or HSAT-derived indices quantifying nocturnal hypoxemia with global burden/individual markers of CSVD on MRI. Indices included ox"],"journal":["Frontiers in neurology"],"pagination":["956208"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9452809"],"repository":["biostudies-literature"],"pubmed_title":["Associations of sleep apnea risk and oxygen desaturation indices with cerebral small vessel disease burden in patients with stroke."],"pmcid":["PMC9452809"],"pubmed_authors":["Liu X","Mak HK","Ip MS","Lau KK","Lam DC"],"additional_accession":[]},"is_claimable":false,"name":"Associations of sleep apnea risk and oxygen desaturation indices with cerebral small vessel disease burden in patients with stroke.","description":"<h4>Background</h4>Obstructive sleep apnea (OSA) is associated with cerebral small vessel disease (CSVD). Nonetheless, whether OSA-risk determined by a simple screening questionnaire or indices quantifying nocturnal hypoxemia other than the conventional apnea-hypopnea index (AHI) by the home sleep apnea test (HSAT) associated with CSVD burden remains uncertain.<h4>Methods</h4>From 2018 to 2021, we recruited patients with transient ischemic attack (TIA)/minor stroke from the Queen Mary Hospital Acute Stroke Unit and TIA/Stroke Outpatient Clinics. Logistic regression models were applied to determine the association of baseline OSA-risk (on STOP-BANG questionnaire) or HSAT-derived indices quantifying nocturnal hypoxemia with global burden/individual markers of CSVD on MRI. Indices included ox","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-18T22:41:59.232Z","creation":"2025-04-07T10:25:32.165Z"},"accession":"S-EPMC9452809","cross_references":{"pubmed":["36090876"],"doi":["10.3389/fneur.2022.956208"]}}