{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Rupp T"],"pubmed_abstract":["<b>Purpose:</b> Hypoxia is one major environmental factor, supposed to mediate central motor command as well as afferent feedbacks at rest and during exercise. By using a comparison of normobaric (NH) and hypobaric (HH) hypoxia with the same ambient pressure in oxygen, we examined the potential differences on the cerebrovascular and muscular regulation interplay during a self-paced aerobic exercise. <b>Methods:</b> Sixteen healthy subjects performed three cycling time-trials (250 kJ) in three conditions: HH, NH and normobaric normoxia (NN) after 24 h of exposure. Cerebral and muscular oxygenation were assessed by near-infrared spectroscopy, cerebral blood flow by Doppler ultrasound system. Gas exchanges, peripheral oxygen saturation, power output and associated pacing strategies were also "],"journal":["Frontiers in physiology"],"pagination":["893872"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9453479"],"repository":["biostudies-literature"],"pubmed_title":["Brain-muscle interplay during endurance self-paced exercise in normobaric and hypobaric hypoxia."],"pmcid":["PMC9453479"],"pubmed_authors":["Saugy JJ","Rupp T","Bourdillon N","Millet GP"],"additional_accession":[]},"is_claimable":false,"name":"Brain-muscle interplay during endurance self-paced exercise in normobaric and hypobaric hypoxia.","description":"<b>Purpose:</b> Hypoxia is one major environmental factor, supposed to mediate central motor command as well as afferent feedbacks at rest and during exercise. By using a comparison of normobaric (NH) and hypobaric (HH) hypoxia with the same ambient pressure in oxygen, we examined the potential differences on the cerebrovascular and muscular regulation interplay during a self-paced aerobic exercise. <b>Methods:</b> Sixteen healthy subjects performed three cycling time-trials (250 kJ) in three conditions: HH, NH and normobaric normoxia (NN) after 24 h of exposure. Cerebral and muscular oxygenation were assessed by near-infrared spectroscopy, cerebral blood flow by Doppler ultrasound system. Gas exchanges, peripheral oxygen saturation, power output and associated pacing strategies were also ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-05T10:25:54.478Z","creation":"2025-04-05T10:25:54.478Z"},"accession":"S-EPMC9453479","cross_references":{"pubmed":["36091393"],"doi":["10.3389/fphys.2022.893872"]}}