{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lundgren P"],"funding":["Massachusetts Lions Eye Foundation","NEI NIH HHS","Swedish Medical Research Council","National Institutes of Health","NIH HHS","Gothenburg Medical Society and Government"],"pagination":["1515-1525"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9454067"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["111(8)"],"pubmed_abstract":["<h4>Aim</h4>To describe survival and neonatal morbidities in infants born before 24 weeks of gestation during a 12-year period.<h4>Methods</h4>Data were retrieved from national registries and validated in medical files of infants born before 24 weeks of gestation 2007-2018 in Sweden. Temporal changes were evaluated.<h4>Results</h4>In 2007-2018, 282 live births were recorded at 22 weeks and 460 at 23 weeks of gestation. Survival to discharge from hospital of infants born alive at 22 and 23 weeks increased from 20% to 38% (p = 0.006) and from 45% to 67% (p < 0.001) respectively. Caesarean section increased from 12% to 22% (p = 0.038) for infants born at 22 weeks. Neonatal morbidity rates in infants alive at 40 weeks of postmenstrual age (n = 399) were unchanged except for an increase in necr"],"journal":["Acta paediatrica (Oslo, Norway : 1992)"],"pubmed_title":["National cohort of infants born before 24 gestational weeks showed increased survival rates but no improvement in neonatal morbidity."],"pmcid":["PMC9454067"],"funding_grant_id":["ALFGBG-717971","1U54HD090255","EY017017","R01 EY017017","EY030904","R01 EY030904"],"pubmed_authors":["Hellstrom A","Morsing E","Johnson M","Rakow A","Hellstrom-Westas L","Savman K","Hard AL","Jacobson L","Holmstrom G","Lundgren P","Smith LE","Nilsson S"],"additional_accession":[]},"is_claimable":false,"name":"National cohort of infants born before 24 gestational weeks showed increased survival rates but no improvement in neonatal morbidity.","description":"<h4>Aim</h4>To describe survival and neonatal morbidities in infants born before 24 weeks of gestation during a 12-year period.<h4>Methods</h4>Data were retrieved from national registries and validated in medical files of infants born before 24 weeks of gestation 2007-2018 in Sweden. Temporal changes were evaluated.<h4>Results</h4>In 2007-2018, 282 live births were recorded at 22 weeks and 460 at 23 weeks of gestation. Survival to discharge from hospital of infants born alive at 22 and 23 weeks increased from 20% to 38% (p = 0.006) and from 45% to 67% (p < 0.001) respectively. Caesarean section increased from 12% to 22% (p = 0.038) for infants born at 22 weeks. Neonatal morbidity rates in infants alive at 40 weeks of postmenstrual age (n = 399) were unchanged except for an increase in necr","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-27T02:53:03.21Z","creation":"2025-04-06T18:41:57.95Z"},"accession":"S-EPMC9454067","cross_references":{"pubmed":["35395120"],"doi":["10.1111/apa.16354"]}}