{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kiki GAA"],"funding":["Bourses de recherche doctorale et postdoctorale « Eugen Ionescu »"],"pagination":["5445"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9457916"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["27(17)"],"pubmed_abstract":["<i>Dichrostachys cinerea</i> (L.) Wigth & Arn. (DC) is widely used in traditional medicine against several inflammatory diseases, especially rheumatoid arthritis, because of its antioxidant and anti-inflammatory effects. This study aimed to characterize the polyphenol-rich DC fruit extracts and investigate the analgesic, anti-inflammatory, and antioxidant effects in a rat inflammation model induced by complete Freund's adjuvant (CFA). Water and ethanolic extracts were characterized using liquid chromatography coupled with mass spectrometry (LC-MS), Fourier-transform infrared (FTIR) spectroscopy, and gas chromatography coupled with mass spectrometry (GC-MS). The polyphenol-rich extracts were administered in three different concentrations for 30 days. Pain threshold, thermal hyperalgesia, ed"],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["Polyphenols from <i>Dichrostachys cinerea</i> Fruits Anti-Inflammatory, Analgesic, and Antioxidant Capacity in Freund's Adjuvant-Induced Arthritic Rat Model."],"pmcid":["PMC9457916"],"funding_grant_id":["12/2020"],"pubmed_authors":["Mathieu Z","Buzoianu AD","Parvu AE","Chedea VS","Bocsan IC","Kiki GAA","Pop RM","Sabin O","Socaci SA","Francis T","Finsia E"],"additional_accession":[]},"is_claimable":false,"name":"Polyphenols from <i>Dichrostachys cinerea</i> Fruits Anti-Inflammatory, Analgesic, and Antioxidant Capacity in Freund's Adjuvant-Induced Arthritic Rat Model.","description":"<i>Dichrostachys cinerea</i> (L.) Wigth & Arn. (DC) is widely used in traditional medicine against several inflammatory diseases, especially rheumatoid arthritis, because of its antioxidant and anti-inflammatory effects. This study aimed to characterize the polyphenol-rich DC fruit extracts and investigate the analgesic, anti-inflammatory, and antioxidant effects in a rat inflammation model induced by complete Freund's adjuvant (CFA). Water and ethanolic extracts were characterized using liquid chromatography coupled with mass spectrometry (LC-MS), Fourier-transform infrared (FTIR) spectroscopy, and gas chromatography coupled with mass spectrometry (GC-MS). The polyphenol-rich extracts were administered in three different concentrations for 30 days. Pain threshold, thermal hyperalgesia, ed","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-18T18:24:11.232Z","creation":"2025-04-07T05:59:56.952Z"},"accession":"S-EPMC9457916","cross_references":{"pubmed":["36080212"],"doi":["10.3390/molecules27175445"]}}