{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gatz M"],"funding":["NIA NIH HHS","National Institutes of Health"],"pagination":["44-55"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9458772"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(1)"],"pubmed_abstract":["<h4>Introduction</h4>We evaluated the prevalence of dementia and mild cognitive impairment (MCI) in indigenous Tsimane and Moseten, who lead a subsistence lifestyle.<h4>Methods</h4>Participants from population-based samples ≥ 60 years of age (n = 623) were assessed using adapted versions of the Modified Mini-Mental State Examination, informant interview, longitudinal cognitive testing and brain computed tomography (CT) scans.<h4>Results</h4>Tsimane exhibited five cases of dementia (among n = 435; crude prevalence = 1.2%, 95% confidence interval [CI]: 0.4, 2.7); Moseten exhibited one case (among n = 169; crude prevalence = 0.6%, 95% CI: 0.0, 3.2), all age ≥ 80 years. Age-standardized MCI prevalence was 7.7% (95% CI: 5.2, 10.3) in Tsimane and 9.8% (95% CI: 4.9, 14.6) in Moseten. Cognitive im"],"journal":["Alzheimer's & dementia : the journal of the Alzheimer's Association"],"pubmed_title":["Prevalence of dementia and mild cognitive impairment in indigenous Bolivian forager-horticulturalists."],"pmcid":["PMC9458772"],"funding_grant_id":["R01 AG054442","P30 AG066530","RF1 AG054442","RF1 AG 054442","P01 AG055367"],"pubmed_authors":["Kraft TS","Trumble BC","Walters EE","Sutherland JD","Copajira Adrian J","Eid Rodriguez D","Rowan CJ","Bani Cuata J","Thompson RC","Hooper PL","Gurven MD","Barisano G","Stieglitz J","Gatz M","Garcia AR","Allam AH","Seabright E","Miyamoto MI","Quispe Gutierrez R","Borenstein AR","Thomas GS","Michalik DE","Finch CE","Kaplan H","Cummings DK","Chui HC","Wann LS","Sutherland ML","Law EM","Irimia A","Mack WJ"],"additional_accession":[]},"is_claimable":false,"name":"Prevalence of dementia and mild cognitive impairment in indigenous Bolivian forager-horticulturalists.","description":"<h4>Introduction</h4>We evaluated the prevalence of dementia and mild cognitive impairment (MCI) in indigenous Tsimane and Moseten, who lead a subsistence lifestyle.<h4>Methods</h4>Participants from population-based samples ≥ 60 years of age (n = 623) were assessed using adapted versions of the Modified Mini-Mental State Examination, informant interview, longitudinal cognitive testing and brain computed tomography (CT) scans.<h4>Results</h4>Tsimane exhibited five cases of dementia (among n = 435; crude prevalence = 1.2%, 95% confidence interval [CI]: 0.4, 2.7); Moseten exhibited one case (among n = 169; crude prevalence = 0.6%, 95% CI: 0.0, 3.2), all age ≥ 80 years. Age-standardized MCI prevalence was 7.7% (95% CI: 5.2, 10.3) in Tsimane and 9.8% (95% CI: 4.9, 14.6) in Moseten. Cognitive im","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2026-07-14T21:05:53.994Z","creation":"2025-02-18T23:25:54.459Z"},"accession":"S-EPMC9458772","cross_references":{"pubmed":["35262289"],"doi":["10.1002/alz.12626"]}}