biostudies-literatureGatz MNIA NIH HHSNational Institutes of Health44-55https://www.ebi.ac.uk/biostudies/studies/S-EPMC9458772biostudies-literatureUnknown19(1)<h4>Introduction</h4>We evaluated the prevalence of dementia and mild cognitive impairment (MCI) in indigenous Tsimane and Moseten, who lead a subsistence lifestyle.<h4>Methods</h4>Participants from population-based samples ≥ 60 years of age (n = 623) were assessed using adapted versions of the Modified Mini-Mental State Examination, informant interview, longitudinal cognitive testing and brain computed tomography (CT) scans.<h4>Results</h4>Tsimane exhibited five cases of dementia (among n = 435; crude prevalence = 1.2%, 95% confidence interval [CI]: 0.4, 2.7); Moseten exhibited one case (among n = 169; crude prevalence = 0.6%, 95% CI: 0.0, 3.2), all age ≥ 80 years. Age-standardized MCI prevalence was 7.7% (95% CI: 5.2, 10.3) in Tsimane and 9.8% (95% CI: 4.9, 14.6) in Moseten. Cognitive imAlzheimer's & dementia : the journal of the Alzheimer's AssociationPrevalence of dementia and mild cognitive impairment in indigenous Bolivian forager-horticulturalists.PMC9458772R01 AG054442P30 AG066530RF1 AG054442RF1 AG 054442P01 AG055367Kraft TSTrumble BCWalters EESutherland JDCopajira Adrian JEid Rodriguez DRowan CJBani Cuata JThompson RCHooper PLGurven MDBarisano GStieglitz JGatz MGarcia ARAllam AHSeabright EMiyamoto MIQuispe Gutierrez RBorenstein ARThomas GSMichalik DEFinch CEKaplan HCummings DKChui HCWann LSSutherland MLLaw EMIrimia AMack WJfalsePrevalence of dementia and mild cognitive impairment in indigenous Bolivian forager-horticulturalists.<h4>Introduction</h4>We evaluated the prevalence of dementia and mild cognitive impairment (MCI) in indigenous Tsimane and Moseten, who lead a subsistence lifestyle.<h4>Methods</h4>Participants from population-based samples ≥ 60 years of age (n = 623) were assessed using adapted versions of the Modified Mini-Mental State Examination, informant interview, longitudinal cognitive testing and brain computed tomography (CT) scans.<h4>Results</h4>Tsimane exhibited five cases of dementia (among n = 435; crude prevalence = 1.2%, 95% confidence interval [CI]: 0.4, 2.7); Moseten exhibited one case (among n = 169; crude prevalence = 0.6%, 95% CI: 0.0, 3.2), all age ≥ 80 years. Age-standardized MCI prevalence was 7.7% (95% CI: 5.2, 10.3) in Tsimane and 9.8% (95% CI: 4.9, 14.6) in Moseten. Cognitive im2023-01-01T00:00:00Z2023 Jan2026-07-14T21:05:53.994Z2025-02-18T23:25:54.459ZS-EPMC94587723526228910.1002/alz.12626