biostudies-literatureUnknown7(9)Pinto SW<h4>Introduction</h4>Post-streptococcal glomerulonephritis (PSGN) has a good prognosis in children, but few studies have evaluated the long-term renal outcomes in adults with PSGN.<h4>Methods</h4>In a follow-up study, 47 predominantly adult patients with PSGN due to group C <i>Streptococcus zooepidemicus</i> were reassessed 20 years after an outbreak in Nova Serrana, Brazil. We evaluated clinical characteristics, renal outcomes, and the trajectory of the estimated glomerular filtration rate (eGFR) by the creatinine-based chronic kidney disease-epidemiology collaboration equation from 5 follow-up assessments. Logistic regression and mixed-effects regression were used in the analysis.<h4>Results</h4>After 20 years, the participants' mean age was 56.6±15.1 years. Thirty-four (72%) patients haKidney international reports2029-2038https://www.ebi.ac.uk/biostudies/studies/S-EPMC9458988biostudies-literatureTwenty-year Follow-up of Patients With Epidemic Glomerulonephritis due to <i>Streptococcus zooepidemicus</i> in Brazil.PMC9458988Pinto SWSesso Rde Abreu TTOtoni Ado Nascimento Lima HKoch Nogueira PCfalseTwenty-year Follow-up of Patients With Epidemic Glomerulonephritis due to <i>Streptococcus zooepidemicus</i> in Brazil.<h4>Introduction</h4>Post-streptococcal glomerulonephritis (PSGN) has a good prognosis in children, but few studies have evaluated the long-term renal outcomes in adults with PSGN.<h4>Methods</h4>In a follow-up study, 47 predominantly adult patients with PSGN due to group C <i>Streptococcus zooepidemicus</i> were reassessed 20 years after an outbreak in Nova Serrana, Brazil. We evaluated clinical characteristics, renal outcomes, and the trajectory of the estimated glomerular filtration rate (eGFR) by the creatinine-based chronic kidney disease-epidemiology collaboration equation from 5 follow-up assessments. Logistic regression and mixed-effects regression were used in the analysis.<h4>Results</h4>After 20 years, the participants' mean age was 56.6±15.1 years. Thirty-four (72%) patients ha2022-01-01T00:00:00Z2022 Sep2025-04-05T10:25:36.269Z2025-04-05T10:25:36.269ZS-EPMC94589883609050310.1016/j.ekir.2022.06.011