biostudies-literatureUnknown13(4)de Jong MHS<h4>Background</h4>The incidence of lymph node metastases is closely related to the T-stage, and therefore Eastern guidelines advice a D1 lymphadenectomy for early gastric cancer and a D2 lymphadenectomy for advanced gastric cancer. The aim of this study was to compare the lymph node metastases rate in the stations dissected with a D2-lymphadenectomy (stations 8-12) yet spared with a D1-lymphadenectomy, between different T-stages in a Western patient cohort.<h4>Methods</h4>For this retrospective study, patients who underwent a gastrectomy in the Amsterdam University Medical Center (UMC), location Academic Medical Center (AMC), between 2011 and 2016 were identified from a prospectively maintained database. The primary outcome was to compare the rate of lymph node metastases in station 8-12 Journal of gastrointestinal oncology1605-1615https://www.ebi.ac.uk/biostudies/studies/S-EPMC9459217biostudies-literatureLymph node metastases rate of locoregional and non-locoregional lymph node stations in gastric cancer.PMC9459217Draaisma WAvan Berge Henegouwen MIGisbertz SSde Jong MHSfalseLymph node metastases rate of locoregional and non-locoregional lymph node stations in gastric cancer.<h4>Background</h4>The incidence of lymph node metastases is closely related to the T-stage, and therefore Eastern guidelines advice a D1 lymphadenectomy for early gastric cancer and a D2 lymphadenectomy for advanced gastric cancer. The aim of this study was to compare the lymph node metastases rate in the stations dissected with a D2-lymphadenectomy (stations 8-12) yet spared with a D1-lymphadenectomy, between different T-stages in a Western patient cohort.<h4>Methods</h4>For this retrospective study, patients who underwent a gastrectomy in the Amsterdam University Medical Center (UMC), location Academic Medical Center (AMC), between 2011 and 2016 were identified from a prospectively maintained database. The primary outcome was to compare the rate of lymph node metastases in station 8-12 2022-01-01T00:00:00Z2022 Aug2025-04-18T22:42:27.856Z2025-04-07T10:28:37.147ZS-EPMC94592173609235310.21037/jgo-22-147