{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ye B"],"funding":["Zhejiang Academy of Forestry Project"],"pagination":["4"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9459437"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["22(5)"],"pubmed_abstract":["In this study, a novel β-1,3-glucan recognition protein gene (β-GRP) was identified from Melanotus cribricollis, and its potential role in the immune response was investigated. The full length of β-GRP cDNA (Accession Number: MT941530) was 1644 bp, encoding a protein composed of 428 amino acids. The theoretical molecular weight and the isoelectric point were 51.53 kDa and 6.17, respectively. The amino acid sequence of β-GRP from M. cribricollis was closely related to that of. β-GRP-like from Photinus pyralis, and was predicted to contain conserved GH16 domain without glucanase active site. The results of real-time quantitative PCR showed that fungal infection of Metarhizium pingshaense may significantly upregulated the expression level of β-GRP gene. The RNAi suppression of β-GRP gene expr"],"journal":["Journal of insect science (Online)"],"pubmed_title":["Cloning and Functional Characterization of a Novel β-GRP Gene From Melanotus cribricollis."],"pmcid":["PMC9459437"],"funding_grant_id":["2021F1065-2"],"pubmed_authors":["Li H","Shen J","Zhang Y","Ye B","Song Q","Wu C","Shu J"],"additional_accession":[]},"is_claimable":false,"name":"Cloning and Functional Characterization of a Novel β-GRP Gene From Melanotus cribricollis.","description":"In this study, a novel β-1,3-glucan recognition protein gene (β-GRP) was identified from Melanotus cribricollis, and its potential role in the immune response was investigated. The full length of β-GRP cDNA (Accession Number: MT941530) was 1644 bp, encoding a protein composed of 428 amino acids. The theoretical molecular weight and the isoelectric point were 51.53 kDa and 6.17, respectively. The amino acid sequence of β-GRP from M. cribricollis was closely related to that of. β-GRP-like from Photinus pyralis, and was predicted to contain conserved GH16 domain without glucanase active site. The results of real-time quantitative PCR showed that fungal infection of Metarhizium pingshaense may significantly upregulated the expression level of β-GRP gene. The RNAi suppression of β-GRP gene expr","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-05-29T16:11:26.403Z","creation":"2025-04-06T01:49:59.57Z"},"accession":"S-EPMC9459437","cross_references":{"pubmed":["36082677"],"doi":["10.1093/jisesa/ieac051"]}}