{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["17(6)"],"submitter":["De Giorgi A"],"pubmed_abstract":["<h4>Introduction</h4>Data from the \"Trattamento Ormonale nello Scompenso CArdiaco\" (T.O.S.CA) registry showed that heart failure (HF) represents a complex clinical syndrome with different hormonal alterations. Renal failure represents a frequent complication in HF. We evaluated the relationship between renal function and insuline-like growth factor-1 (IGF-1) deficiency and its impact on cardiovascular mortality (CVM) in patients enrolled in the T.O.S.CA. registry.<h4>Methods</h4>At the enrolment, all subjects underwent chemistry examinations, including circulating hormones and cardiovascular functional tests. COX regression analysis was used to evaluate factors related to CVM during the follow-up period in all populations, in high-risk patients and in the young-adult population. Also, we e"],"journal":["Internal and emergency medicine"],"pagination":["1651-1660"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9463276"],"repository":["biostudies-literature"],"pubmed_title":["Insulin-like growth factor-1 (IGF-1) as predictor of cardiovascular mortality in heart failure patients: data from the T.O.S.CA. registry."],"pmcid":["PMC9463276"],"pubmed_authors":["D'Assante R","Calabro P","Casaretti L","Frigiola A","Calabro R","Puzzo A","Mancini A","Favuzzi AMR","Sorrentino MR","Maddaloni V","Bruzzese D","Gargiulo P","Scarafile R","De Giorgi A","Malandrino D","ArcopintoSalzano MA","Stagnaro FM","Generali T","Vergani E","Leone M","D'Andrea A","Masarone D","Perticone F","Cittadini A","Sciacqua A","Volterrani M","Bruno C","Castello R","Passantino A","Giacomazzi F","Schiavo A","Belfiore A","Paolillo S","Ragusa L","Modesti PA","Manfredini R","Malizia G","Iacoviello M","Suzuki T","Vriz O","Napoli R","Valente P","De Vincentiis C","Marra AM","Cimellaro A","Sci-Acqua A","Di Segni C","Raparelli V","Maiello C","Malinconico M","Cacciatore F","Fabbian F","Salzano A","Citro R","Amarelli C","Garofalo P","Rengo G","Bossone E","Limongelli G","Ferrara F","Matarazzo M","Colao A","Campo M","Carbone L","Arcopinto M","T.O.S.CA. Investigators","Guastalamacchia E","Pacileo G","Ballotta A","Heaney LM","Monti MG","Caliendo L","Russo V","Frigo A","Sacca L","Triggiani V","Mattucci I","Filardi PP"],"additional_accession":[]},"is_claimable":false,"name":"Insulin-like growth factor-1 (IGF-1) as predictor of cardiovascular mortality in heart failure patients: data from the T.O.S.CA. registry.","description":"<h4>Introduction</h4>Data from the \"Trattamento Ormonale nello Scompenso CArdiaco\" (T.O.S.CA) registry showed that heart failure (HF) represents a complex clinical syndrome with different hormonal alterations. Renal failure represents a frequent complication in HF. We evaluated the relationship between renal function and insuline-like growth factor-1 (IGF-1) deficiency and its impact on cardiovascular mortality (CVM) in patients enrolled in the T.O.S.CA. registry.<h4>Methods</h4>At the enrolment, all subjects underwent chemistry examinations, including circulating hormones and cardiovascular functional tests. COX regression analysis was used to evaluate factors related to CVM during the follow-up period in all populations, in high-risk patients and in the young-adult population. Also, we e","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2026-05-27T23:48:49.07Z","creation":"2024-11-19T16:34:04.074Z"},"accession":"S-EPMC9463276","cross_references":{"pubmed":["35445917"],"doi":["10.1007/s11739-022-02980-4"]}}