biostudies-literatureUnknown13Gao XActivity of BC1 complex kinase (ABC1K) serves as an atypical kinase family involved in plant stress resistance. This study identified 44 <i>ABC1K</i> genes in the wheat genome, which contained three clades (I-III). <i>TaABC1K</i> genes generally had similar structural features, but differences were present in motif and exon compositions from different clade members. More type II functional divergence sites were detected between clade I and clade III and no positive selection site were found in <i>TaABC1K</i> family. The three-dimensional structure prediction by Alphafold2 showed that TaABC1K proteins had more α-helixes with a relatively even distribution, and different clade members had differences in the content of secondary structures. The <i>cis</i>-acting element analysis showed that <Frontiers in plant science991171https://www.ebi.ac.uk/biostudies/studies/S-EPMC9465391biostudies-literatureGenome-wide identification of wheat ABC1K gene family and functional dissection of <i>TaABC1K3</i> and <i>TaABC1K6</i> involved in drought tolerance.PMC9465391Liu JHu YZou RGao XSun HYan YDuan WfalseGenome-wide identification of wheat ABC1K gene family and functional dissection of <i>TaABC1K3</i> and <i>TaABC1K6</i> involved in drought tolerance.Activity of BC1 complex kinase (ABC1K) serves as an atypical kinase family involved in plant stress resistance. This study identified 44 <i>ABC1K</i> genes in the wheat genome, which contained three clades (I-III). <i>TaABC1K</i> genes generally had similar structural features, but differences were present in motif and exon compositions from different clade members. More type II functional divergence sites were detected between clade I and clade III and no positive selection site were found in <i>TaABC1K</i> family. The three-dimensional structure prediction by Alphafold2 showed that TaABC1K proteins had more α-helixes with a relatively even distribution, and different clade members had differences in the content of secondary structures. The <i>cis</i>-acting element analysis showed that <2022-01-01T00:00:00Z20222025-04-22T02:16:39.018Z2024-11-12T22:02:59.401ZS-EPMC94653913610569910.3389/fpls.2022.991171