biostudies-literatureKim EKKorea Health Industry Development Institute776https://www.ebi.ac.uk/biostudies/studies/S-EPMC9476301biostudies-literatureUnknown23(1)<h4>Background</h4>Cardiac evaluation using transthoracic echocardiography before noncardiac surgery is common in real-world practice. However, evidence supporting preoperative echocardiography is lacking. This study aims to evaluate the additional benefit of preoperative echocardiography in predicting postoperative cardiovascular events (CVE) in noncardiac surgery.<h4>Methods</h4>This study is designed as a multicenter, prospective study to assess the utility of preoperative echocardiography in patients undergoing intermediate- or high-risk noncardiac surgery. This trial comprises two studies: (1) a randomized controlled trial (RCT) for patients undergoing intermediate-risk surgery with fewer than three clinical risk factors from the revised cardiac risk index (intermediate-risk group) anTrialsPRE-OPerative ECHOcardiograhy for prevention of cardiovascular events after non-cardiac surgery in intermediate- and high-risk patients: protocol for a low-interventional, mixed-cohort prospective study design (PREOP-ECHO).PMC9476301HI19C0481, HC20C0082Kim EKNa JOKim MNCho GYShin SHChoi EYLee HSCho IPark YHChoi JHKim KHHwang JWKim DHPark GKim HKChoi HMKang DHLee SHHong JYLee SEPark DGJung HOSohn ISPark CSHan DWPark THShin MSfalsePRE-OPerative ECHOcardiograhy for prevention of cardiovascular events after non-cardiac surgery in intermediate- and high-risk patients: protocol for a low-interventional, mixed-cohort prospective study design (PREOP-ECHO).<h4>Background</h4>Cardiac evaluation using transthoracic echocardiography before noncardiac surgery is common in real-world practice. However, evidence supporting preoperative echocardiography is lacking. This study aims to evaluate the additional benefit of preoperative echocardiography in predicting postoperative cardiovascular events (CVE) in noncardiac surgery.<h4>Methods</h4>This study is designed as a multicenter, prospective study to assess the utility of preoperative echocardiography in patients undergoing intermediate- or high-risk noncardiac surgery. This trial comprises two studies: (1) a randomized controlled trial (RCT) for patients undergoing intermediate-risk surgery with fewer than three clinical risk factors from the revised cardiac risk index (intermediate-risk group) an2022-01-01T00:00:00Z2022 Sep2025-04-04T22:36:29.205Z2024-11-20T21:42:36.161ZS-EPMC94763013610471410.1186/s13063-022-06701-2