biostudies-literatureUnknown14Jazieh AR<h4>Background</h4>Tyrosine kinase inhibitors (TKIs) are the standard of care for resectable and metastatic non-small-cell lung cancer (NSCLC) harbouring epidermal growth factor receptor (EGFR) mutations (EGFRm). We describe the real-world practice of EGFRm testing, prevalence, treatment and outcomes in EGFRm stage III NSCLC from a multi-country, observational study.<h4>Methods</h4>The KINDLE study retrospectively captured diagnostic information, treatments and survival outcomes in patients with stage III NSCLC from January 2013 to December 2017. Baseline characteristics and treatments were described and real-world outcomes from initial therapy were analysed using Kaplan-Meier methods.<h4>Results</h4>A total of 3151 patients were enrolled across three regions: Asia (<i>n</i> = 1874), MiddlTherapeutic advances in medical oncology17588359221122720https://www.ebi.ac.uk/biostudies/studies/S-EPMC9478745biostudies-literatureReal-world global data on targeting epidermal growth factor receptor mutations in stage III non-small-cell lung cancer: the results of the KINDLE study.PMC9478745Huggenberger RJazieh ARCho BCOnal HCPrabhash KSoo RAKumar ATan DSfalseReal-world global data on targeting epidermal growth factor receptor mutations in stage III non-small-cell lung cancer: the results of the KINDLE study.<h4>Background</h4>Tyrosine kinase inhibitors (TKIs) are the standard of care for resectable and metastatic non-small-cell lung cancer (NSCLC) harbouring epidermal growth factor receptor (EGFR) mutations (EGFRm). We describe the real-world practice of EGFRm testing, prevalence, treatment and outcomes in EGFRm stage III NSCLC from a multi-country, observational study.<h4>Methods</h4>The KINDLE study retrospectively captured diagnostic information, treatments and survival outcomes in patients with stage III NSCLC from January 2013 to December 2017. Baseline characteristics and treatments were described and real-world outcomes from initial therapy were analysed using Kaplan-Meier methods.<h4>Results</h4>A total of 3151 patients were enrolled across three regions: Asia (<i>n</i> = 1874), Middl2022-01-01T00:00:00Z20222026-05-28T05:42:04.38Z2025-02-19T04:39:03.193ZS-EPMC94787453611964110.1177/17588359221122720