{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Duindam HB"],"funding":["ZonMw"],"pagination":["100513"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9482799"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25"],"pubmed_abstract":["<h4>Background and objectives</h4>Long-term cognitive performance data in former critically ill COVID-19 patients are sparse. Current evidence suggests that cognitive decline is related to neuroinflammation, which might be attenuated by COVID-19 related anti-inflammatory therapies. The objective of this prospective cohort study was to study long term cognitive outcomes following severe COVID-19 and the relation to anti-inflammatory therapies.<h4>Methods</h4>Prospective observational cohort of patients that survived an intensive care unit (ICU) admission due to severe COVID-19. Six months after hospital discharge, we extensively assessed both objective cognitive functioning and subjective cognitive complaints. Furthermore, patients were stratified in cohorts according to their anti-inflamma"],"journal":["Brain, behavior, & immunity - health"],"pubmed_title":["Long-term cognitive performance and its relation to anti-inflammatory therapy in a cohort of survivors of severe COVID-19."],"pmcid":["PMC9482799"],"funding_grant_id":["90715610"],"pubmed_authors":["Kessels RPC","Pickkers P","van den Borst B","Abdo WF","Duindam HB"],"additional_accession":[]},"is_claimable":false,"name":"Long-term cognitive performance and its relation to anti-inflammatory therapy in a cohort of survivors of severe COVID-19.","description":"<h4>Background and objectives</h4>Long-term cognitive performance data in former critically ill COVID-19 patients are sparse. Current evidence suggests that cognitive decline is related to neuroinflammation, which might be attenuated by COVID-19 related anti-inflammatory therapies. The objective of this prospective cohort study was to study long term cognitive outcomes following severe COVID-19 and the relation to anti-inflammatory therapies.<h4>Methods</h4>Prospective observational cohort of patients that survived an intensive care unit (ICU) admission due to severe COVID-19. Six months after hospital discharge, we extensively assessed both objective cognitive functioning and subjective cognitive complaints. Furthermore, patients were stratified in cohorts according to their anti-inflamma","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-27T02:55:06.547Z","creation":"2024-10-15T07:24:13.62Z"},"accession":"S-EPMC9482799","cross_references":{"pubmed":["36159208"],"doi":["10.1016/j.bbih.2022.100513"]}}