{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang X"],"funding":["FDA HHS"],"pagination":["1851-1861"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9486596"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["152(8)"],"pubmed_abstract":["<h4>Background</h4>Diets emphasizing unsaturated fat and high fiber are associated with reducing cardiometabolic risk factors. Avocados are rich in MUFA and PUFA fats and fiber.<h4>Objectives</h4>Assess replacement of carbohydrate energy with avocado energy for 12 wk on glucose homeostasis and cardiometabolic risk factors in self-selecting free-living adults who are overweight or with obesity and have insulin resistance.<h4>Methods</h4>In a single-center, randomized, 2-arm, controlled, 12-wk parallel trial, adults [n = 93; male/female: 39/54; mean ± SD age: 42 ± 12 y; BMI: 32.6 ± 3.9 (in kg/m2);  HOMA-IR: 2.7 ± 1.7] were counseled to exchange avocado (AV) or control food (C; low fat, low fiber, energy matched) for carbohydrate food in their usual diet for 12 wk. The primary outcome was the"],"journal":["The Journal of nutrition"],"pubmed_title":["Avocado Consumption for 12 Weeks and Cardiometabolic Risk Factors: A Randomized Controlled Trial in Adults with Overweight or Obesity and Insulin Resistance."],"pmcid":["PMC9486596"],"funding_grant_id":["U19 FD005322"],"pubmed_authors":["Burton-Freeman B","Zhang X","Edirisinghe I","Xiao D","Guzman G"],"additional_accession":[]},"is_claimable":false,"name":"Avocado Consumption for 12 Weeks and Cardiometabolic Risk Factors: A Randomized Controlled Trial in Adults with Overweight or Obesity and Insulin Resistance.","description":"<h4>Background</h4>Diets emphasizing unsaturated fat and high fiber are associated with reducing cardiometabolic risk factors. Avocados are rich in MUFA and PUFA fats and fiber.<h4>Objectives</h4>Assess replacement of carbohydrate energy with avocado energy for 12 wk on glucose homeostasis and cardiometabolic risk factors in self-selecting free-living adults who are overweight or with obesity and have insulin resistance.<h4>Methods</h4>In a single-center, randomized, 2-arm, controlled, 12-wk parallel trial, adults [n = 93; male/female: 39/54; mean ± SD age: 42 ± 12 y; BMI: 32.6 ± 3.9 (in kg/m2);  HOMA-IR: 2.7 ± 1.7] were counseled to exchange avocado (AV) or control food (C; low fat, low fiber, energy matched) for carbohydrate food in their usual diet for 12 wk. The primary outcome was the","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2026-05-27T18:53:21.402Z","creation":"2025-04-05T23:48:36.893Z"},"accession":"S-EPMC9486596","cross_references":{"pubmed":["35700149"],"doi":["10.1093/jn/nxac126"]}}