{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Wang C"],"pubmed_abstract":["<h4>Purpose</h4>Previous studies have suggested a link between cardiovascular disease (CVD) and the subsequent development of lung cancer. However, empirical evidence on the association of CVDs, particularly type-specific CVDs, with lung cancer incidence and survival remains limited.<h4>Methods</h4>The cohort study included 306,285 patients with CVD and 1,222,140 individuals without CVD. We performed stratified Cox regression to estimate the hazard ratio (HR).<h4>Results</h4>During up to 42 years of follow-up, 243 (0.08%) and 537 (0.04%) participants were diagnosed with lung cancer among CVD patients and matched individuals, respectively. Patients with CVD had a 67% increased risk of lung cancer (HR: 1.67, 95% confidence interval [CI]: 1.42-1.96). The increased risks were observed in patie"],"journal":["Frontiers in oncology"],"pagination":["950971"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9486704"],"repository":["biostudies-literature"],"pubmed_title":["Cardiovascular disease and risk of lung cancer incidence and mortality: A nationwide matched cohort study."],"pmcid":["PMC9486704"],"pubmed_authors":["Huang C","Li J","Wang C","Wei D","Lu D","Qin G","Cronin-Fenton D","Liew Z","Yu Y"],"additional_accession":[]},"is_claimable":false,"name":"Cardiovascular disease and risk of lung cancer incidence and mortality: A nationwide matched cohort study.","description":"<h4>Purpose</h4>Previous studies have suggested a link between cardiovascular disease (CVD) and the subsequent development of lung cancer. However, empirical evidence on the association of CVDs, particularly type-specific CVDs, with lung cancer incidence and survival remains limited.<h4>Methods</h4>The cohort study included 306,285 patients with CVD and 1,222,140 individuals without CVD. We performed stratified Cox regression to estimate the hazard ratio (HR).<h4>Results</h4>During up to 42 years of follow-up, 243 (0.08%) and 537 (0.04%) participants were diagnosed with lung cancer among CVD patients and matched individuals, respectively. Patients with CVD had a 67% increased risk of lung cancer (HR: 1.67, 95% confidence interval [CI]: 1.42-1.96). The increased risks were observed in patie","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-19T21:43:12.443Z","creation":"2025-04-19T21:43:12.443Z"},"accession":"S-EPMC9486704","cross_references":{"pubmed":["36147909"],"doi":["10.3389/fonc.2022.950971"]}}