{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["81"],"submitter":["Khan QA"],"pubmed_abstract":["<h4>Background</h4>Non-Hodgkin's lymphoma (NHL) is a monoclonal proliferation of lymphoid cells from B lineage. Although NHLs are primarily hematological tumors of lymph nodes but rarely can involve extranodal sites such as the spleen.<h4>Case report</h4>A 29-year-old female patient presented with low-grade fever, cough, anemia, weight loss, tender left hypochondrium, and splenomegaly. A hypodense lesion in the spleen with central necrosis, having strong positivity for common leukocyte antigen (LCA), CD 20, and CD 10, led to a diffuse large B cell lymphoma diagnosis. The patient had an excellent clinical post-splenectomy response to combination chemotherapy and immunotherapy.<h4>Conclusion</h4>NHL can present with symptomatic extra-nodal involvement without enlarged lymph nodes."],"journal":["Annals of medicine and surgery (2012)"],"pagination":["104449"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9486706"],"repository":["biostudies-literature"],"pubmed_title":["Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report."],"pmcid":["PMC9486706"],"pubmed_authors":["Mahfooz RS","Khan QA","Ain HU","Baqi A","Hussien Mohamed Ahmed KA","Asim N","Yousaf Z","Tahir MJ","Mumtaz A","Iram S"],"additional_accession":[]},"is_claimable":false,"name":"Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report.","description":"<h4>Background</h4>Non-Hodgkin's lymphoma (NHL) is a monoclonal proliferation of lymphoid cells from B lineage. Although NHLs are primarily hematological tumors of lymph nodes but rarely can involve extranodal sites such as the spleen.<h4>Case report</h4>A 29-year-old female patient presented with low-grade fever, cough, anemia, weight loss, tender left hypochondrium, and splenomegaly. A hypodense lesion in the spleen with central necrosis, having strong positivity for common leukocyte antigen (LCA), CD 20, and CD 10, led to a diffuse large B cell lymphoma diagnosis. The patient had an excellent clinical post-splenectomy response to combination chemotherapy and immunotherapy.<h4>Conclusion</h4>NHL can present with symptomatic extra-nodal involvement without enlarged lymph nodes.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-25T19:13:47.477Z","creation":"2025-04-06T07:51:23.129Z"},"accession":"S-EPMC9486706","cross_references":{"pubmed":["36147111"],"doi":["10.1016/j.amsu.2022.104449"]}}