biostudies-literatureBayliss EANIA NIH HHSNational Institute on Aging2487-2497https://www.ebi.ac.uk/biostudies/studies/S-EPMC9489620biostudies-literatureUnknown70(9)Interpreting results from deprescribing interventions to generate actionable evidence is challenging owing to inconsistent and heterogeneous outcome definitions between studies. We sought to characterize deprescribing intervention outcomes and recommend approaches to measure outcomes for future studies. A scoping literature review focused on deprescribing interventions for polypharmacy and informed a series of expert panel discussions and recommendations. Twelve experts in deprescribing research, policy, and clinical practice interventions participating in the Measures Workgroup of the US Deprescribing Research Network sought to characterize deprescribing outcomes and recommend approaches to measure outcomes for future studies. The scoping review identified 125 papers reflecting 107 depresJournal of the American Geriatrics SocietyRecommendations for outcome measurement for deprescribing intervention studies.PMC9489620R24 AG064025P30 AG024824R24AG064025Rich MWGleason KEnsrud KEVasilevskis EEBayliss EAGray SLBoyd CMLinsky AMCampbell NLMin LDublin STurner JAlbers KSteinman MAPieper LEMangin DfalseRecommendations for outcome measurement for deprescribing intervention studies.Interpreting results from deprescribing interventions to generate actionable evidence is challenging owing to inconsistent and heterogeneous outcome definitions between studies. We sought to characterize deprescribing intervention outcomes and recommend approaches to measure outcomes for future studies. A scoping literature review focused on deprescribing interventions for polypharmacy and informed a series of expert panel discussions and recommendations. Twelve experts in deprescribing research, policy, and clinical practice interventions participating in the Measures Workgroup of the US Deprescribing Research Network sought to characterize deprescribing outcomes and recommend approaches to measure outcomes for future studies. The scoping review identified 125 papers reflecting 107 depres2022-01-01T00:00:00Z2022 Sep2025-04-04T07:44:10.395Z2025-04-04T07:44:10.395ZS-EPMC94896203564846510.1111/jgs.17894