{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(41)"],"submitter":["Jiang Y"],"pubmed_abstract":["In this study, new magnetic nanoparticles (denotated as Fe<sub>3</sub>O<sub>4</sub>@mSiO<sub>2</sub>-PFIL-Ti<sup>4+</sup>) have been prepared by immobilizing titanium ions with phosphonate functionalized ionic liquid (PFIL) on the wall of core-shell structured mesoporous nanomaterials. The resulting nanoparticles possess large specific surface area, strong hydrophilicity and fast magnetic response. The composites can capture traces of phosphopeptides from the tryptic β-casein digest (0.08 fmol), a digest mixture of β-casein and BSA (1 : 10 000, molar ratio) as well as a blend of β-casein digest and a great quantity of phosphorylated protein (β-casein) and non-phosphorylated protein (BSA) (1 : 2000 : 2000, mass ratio), respectively, showing excellent sensitivity, selectivity and size exclus"],"journal":["RSC advances"],"pagination":["26859-26865"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9490807"],"repository":["biostudies-literature"],"pubmed_title":["Magnetic mesoporous silica nanoparticles modified by phosphonate functionalized ionic liquid for selective enrichment of phosphopeptides."],"pmcid":["PMC9490807"],"pubmed_authors":["Jiang Y","Zhao L","Liang W","Wang Q","Wang B","Liang H","Cui W","Xia C","Yan Y","Feng Q"],"additional_accession":[]},"is_claimable":false,"name":"Magnetic mesoporous silica nanoparticles modified by phosphonate functionalized ionic liquid for selective enrichment of phosphopeptides.","description":"In this study, new magnetic nanoparticles (denotated as Fe<sub>3</sub>O<sub>4</sub>@mSiO<sub>2</sub>-PFIL-Ti<sup>4+</sup>) have been prepared by immobilizing titanium ions with phosphonate functionalized ionic liquid (PFIL) on the wall of core-shell structured mesoporous nanomaterials. The resulting nanoparticles possess large specific surface area, strong hydrophilicity and fast magnetic response. The composites can capture traces of phosphopeptides from the tryptic β-casein digest (0.08 fmol), a digest mixture of β-casein and BSA (1 : 10 000, molar ratio) as well as a blend of β-casein digest and a great quantity of phosphorylated protein (β-casein) and non-phosphorylated protein (BSA) (1 : 2000 : 2000, mass ratio), respectively, showing excellent sensitivity, selectivity and size exclus","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-05T13:27:50.52Z","creation":"2025-04-05T13:27:50.52Z"},"accession":"S-EPMC9490807","cross_references":{"pubmed":["36320858"],"doi":["10.1039/d2ra04609a"]}}