{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["34(2)"],"submitter":["Carter CJ"],"pubmed_abstract":["Cross-reactive immunity occurs when infection with or vaccination against one virus protects against another related family member. A search for homologues of the HIV-1 envelope glycoprotein revealed that it is composed of thousands of intercalating and overlapping viral matches of pentapeptide or longer gapped consensi, belonging to over 70% of the currently sequenced virome, infecting all kingdoms from bacteria to man. It was also highly homologous to proteins from the Visna/Maedi and other ovine viruses, while other proteins (nef/tat/gag/pol) were homologous to proteins from the equine infectious anaemia virus and HTLV-2/HTLV-3 viruses. This phenomenon suggests that horizontal gene transfer from coinfecting RNA and DNA viruses to retroviruses is extensive, providing a route for the subs"],"journal":["Immunopharmacology and immunotoxicology"],"pagination":["222-31"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9491108"],"repository":["biostudies-literature"],"pubmed_title":["Vaccinia and other viruses with available vaccines show marked homology with the HIV-1 envelope glycoprotein: the prospect of using existing vaccines to stem the AIDS pandemic."],"pmcid":["PMC9491108"],"pubmed_authors":["Carter CJ"],"additional_accession":[]},"is_claimable":false,"name":"Vaccinia and other viruses with available vaccines show marked homology with the HIV-1 envelope glycoprotein: the prospect of using existing vaccines to stem the AIDS pandemic.","description":"Cross-reactive immunity occurs when infection with or vaccination against one virus protects against another related family member. A search for homologues of the HIV-1 envelope glycoprotein revealed that it is composed of thousands of intercalating and overlapping viral matches of pentapeptide or longer gapped consensi, belonging to over 70% of the currently sequenced virome, infecting all kingdoms from bacteria to man. It was also highly homologous to proteins from the Visna/Maedi and other ovine viruses, while other proteins (nef/tat/gag/pol) were homologous to proteins from the equine infectious anaemia virus and HTLV-2/HTLV-3 viruses. This phenomenon suggests that horizontal gene transfer from coinfecting RNA and DNA viruses to retroviruses is extensive, providing a route for the subs","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012 Apr","modification":"2025-04-22T21:53:46.302Z","creation":"2025-02-19T01:28:25.979Z"},"accession":"S-EPMC9491108","cross_references":{"pubmed":["21851326"],"doi":["10.3109/08923973.2011.596542"]}}