{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Brashear AM"],"funding":["NIAID NIH HHS","National Institutes of Health"],"pagination":["984394"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9493318"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13"],"pubmed_abstract":["Malaria elimination includes neglected human malaria parasites <i>Plasmodium vivax, Plasmodium ovale</i> spp., and <i>Plasmodium malariae</i>. Biological features such as association with low-density infection and the formation of hypnozoites responsible for relapse make their elimination challenging. Studies on these parasites rely primarily on clinical samples due to the lack of long-term culture techniques. With improved methods to enrich parasite DNA from clinical samples, whole-genome sequencing of the neglected malaria parasites has gained increasing popularity. Population genomics of more than 2200 <i>P. vivax</i> global isolates has improved our knowledge of parasite biology and host-parasite interactions, identified vaccine targets and potential drug resistance markers, and provid"],"journal":["Frontiers in microbiology"],"pubmed_title":["Population genomics in neglected malaria parasites."],"pmcid":["PMC9493318"],"funding_grant_id":["U19 AI089672"],"pubmed_authors":["Brashear AM","Cui L"],"additional_accession":[]},"is_claimable":false,"name":"Population genomics in neglected malaria parasites.","description":"Malaria elimination includes neglected human malaria parasites <i>Plasmodium vivax, Plasmodium ovale</i> spp., and <i>Plasmodium malariae</i>. Biological features such as association with low-density infection and the formation of hypnozoites responsible for relapse make their elimination challenging. Studies on these parasites rely primarily on clinical samples due to the lack of long-term culture techniques. With improved methods to enrich parasite DNA from clinical samples, whole-genome sequencing of the neglected malaria parasites has gained increasing popularity. Population genomics of more than 2200 <i>P. vivax</i> global isolates has improved our knowledge of parasite biology and host-parasite interactions, identified vaccine targets and potential drug resistance markers, and provid","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-08-31T03:18:35.752Z","creation":"2025-04-05T12:32:13.064Z"},"accession":"S-EPMC9493318","cross_references":{"pubmed":["36160257"],"doi":["10.3389/fmicb.2022.984394"]}}