{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["79(11)"],"submitter":["Kendler KS"],"pubmed_abstract":["<h4>Importance</h4>The nature of the genetic relationship between major depression and bipolar disorder remains unclear and might be clarified by considering disorders outside of the mood spectrum.<h4>Objective</h4>To better understand the relationship between genetic liabilities for major depression (MD) and bipolar disorder (BD).<h4>Design, setting, and participants</h4>A cohort study was conducted with data for individuals born in Sweden to Swedish parents from 1960 to 1990, with follow-up through December 31, 2018. The data included family genetic risk scores for MD and BD and International Classification of Diseases codes for a range of disorders as reported in primary care, specialist, and hospital registries. Data analysis was conducted from April 2022 to July 2022.<h4>Exposures</h4"],"journal":["JAMA psychiatry"],"pagination":["1102-1109"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9494271"],"repository":["biostudies-literature"],"pubmed_title":["Risk for Mood, Anxiety, and Psychotic Disorders in Individuals at High and Low Genetic Liability for Bipolar Disorder and Major Depression."],"pmcid":["PMC9494271"],"pubmed_authors":["Sundquist J","Sundquist K","Ohlsson H","Kendler KS"],"additional_accession":[]},"is_claimable":false,"name":"Risk for Mood, Anxiety, and Psychotic Disorders in Individuals at High and Low Genetic Liability for Bipolar Disorder and Major Depression.","description":"<h4>Importance</h4>The nature of the genetic relationship between major depression and bipolar disorder remains unclear and might be clarified by considering disorders outside of the mood spectrum.<h4>Objective</h4>To better understand the relationship between genetic liabilities for major depression (MD) and bipolar disorder (BD).<h4>Design, setting, and participants</h4>A cohort study was conducted with data for individuals born in Sweden to Swedish parents from 1960 to 1990, with follow-up through December 31, 2018. The data included family genetic risk scores for MD and BD and International Classification of Diseases codes for a range of disorders as reported in primary care, specialist, and hospital registries. Data analysis was conducted from April 2022 to July 2022.<h4>Exposures</h4","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-19T17:22:04.813Z","creation":"2025-04-19T17:22:04.813Z"},"accession":"S-EPMC9494271","cross_references":{"pubmed":["36129716"],"doi":["10.1001/jamapsychiatry.2022.2873"]}}