{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Del Coso J"],"funding":["European University of Madrid","Francisco de Vitoria University","Miguel Hernandez University"],"pagination":["1635"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9498709"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(9)"],"pubmed_abstract":["The p.R577X polymorphism (rs1815739) in the <i>ACTN3</i> gene causes individuals with the XX genotype to be deficient in functional α-actinin-3. Previous investigations have found that XX athletes are more prone to suffer non-contact muscle injuries, in comparison with RR and RX athletes who produce a functional α-actinin-3 in their fast-twitch fibers. This investigation aimed to determine the influence of the <i>ACTN3</i> R577X polymorphism on physical performance and injury incidence of players competing in the women's Spanish first division of football (soccer). Using a cross-sectional experiment, football-specific performance and epidemiology of non-contact football-related injuries were recorded in a group of 191 professional football players. <i>ACTN3</i> R577X genotype was obtained "],"journal":["Genes"],"pubmed_title":["Association of the <i>ACTN3</i> rs1815739 Polymorphism with Physical Performance and Injury Incidence in Professional Women Football Players."],"pmcid":["PMC9498709"],"funding_grant_id":["0001","00001"],"pubmed_authors":["Iztueta A","Buil MA","Sanchez-Sanchez J","Rodas G","Del Coso J","Gonzalez-Rodenas J","Gasulla-Angles P","Lopez-Samanes A","Hernandez-Sanchez S","Moreno-Perez V","Lopez P"],"additional_accession":[]},"is_claimable":false,"name":"Association of the <i>ACTN3</i> rs1815739 Polymorphism with Physical Performance and Injury Incidence in Professional Women Football Players.","description":"The p.R577X polymorphism (rs1815739) in the <i>ACTN3</i> gene causes individuals with the XX genotype to be deficient in functional α-actinin-3. Previous investigations have found that XX athletes are more prone to suffer non-contact muscle injuries, in comparison with RR and RX athletes who produce a functional α-actinin-3 in their fast-twitch fibers. This investigation aimed to determine the influence of the <i>ACTN3</i> R577X polymorphism on physical performance and injury incidence of players competing in the women's Spanish first division of football (soccer). Using a cross-sectional experiment, football-specific performance and epidemiology of non-contact football-related injuries were recorded in a group of 191 professional football players. <i>ACTN3</i> R577X genotype was obtained ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-21T14:52:38.945Z","creation":"2025-04-21T14:52:38.945Z"},"accession":"S-EPMC9498709","cross_references":{"pubmed":["36140803"],"doi":["10.3390/genes13091635"]}}