{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["17(9)"],"submitter":["Jung H"],"pubmed_abstract":["<h4>Purpose</h4>To assess the effect of continuous ketamine administration in patients admitted to medical and cardiac intensive care units (ICUs) and received mechanical ventilation support.<h4>Methods</h4>We conducted a retrospective cohort study between March 2012 and June 2020 at an academy-affiliated tertiary hospital. Adult patients who received mechanical ventilation support for over 24 h and continuous ketamine infusion for at least 8 h were included. The primary outcome was immediate hemodynamic safety after continuous ketamine infusion. The secondary outcomes included immediate delirium, pain, and use of sedation.<h4>Results</h4>Of all 12,534 medical and cardiac ICU patients, 564 were eligible for the analysis. Ketamine was used for 33.3 (19.0-67.5) h and the median continuous in"],"journal":["PloS one"],"pagination":["e0274865"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9499237"],"repository":["biostudies-literature"],"pubmed_title":["Safety and feasibility of continuous ketamine infusion for analgosedation in medical and cardiac ICU patients who received mechanical ventilation support: A retrospective cohort study."],"pmcid":["PMC9499237"],"pubmed_authors":["Yang JH","Jung H","Lee J","Ko RE","Ahn HY","Chung CR","Suh GY"],"additional_accession":[]},"is_claimable":false,"name":"Safety and feasibility of continuous ketamine infusion for analgosedation in medical and cardiac ICU patients who received mechanical ventilation support: A retrospective cohort study.","description":"<h4>Purpose</h4>To assess the effect of continuous ketamine administration in patients admitted to medical and cardiac intensive care units (ICUs) and received mechanical ventilation support.<h4>Methods</h4>We conducted a retrospective cohort study between March 2012 and June 2020 at an academy-affiliated tertiary hospital. Adult patients who received mechanical ventilation support for over 24 h and continuous ketamine infusion for at least 8 h were included. The primary outcome was immediate hemodynamic safety after continuous ketamine infusion. The secondary outcomes included immediate delirium, pain, and use of sedation.<h4>Results</h4>Of all 12,534 medical and cardiac ICU patients, 564 were eligible for the analysis. Ketamine was used for 33.3 (19.0-67.5) h and the median continuous in","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-22T10:55:46.831Z","creation":"2025-04-05T23:45:57.916Z"},"accession":"S-EPMC9499237","cross_references":{"pubmed":["36137164"],"doi":["10.1371/journal.pone.0274865"]}}