biostudies-literatureUnknown17(9)Picelli de Azevedo MGIn chronic kidney disease dogs, the inflammatory process increases C-reactive protein concentrations. This study aimed to determine C-reactive protein serum concentrations in stage IV chronic kidney disease dogs treated with intermittent hemodialysis. A prospective cohort study was conducted with 23 dogs allocated into three groups: control group (CG, n = 7), intermittent hemodialysis group (IHG, n = 8) and clinical treatment group (CTG, n = 8), both comprised of stage IV chronic kidney disease dogs. One blood sample from CG (initial evaluation) and two samples from IHG and CTG (first- and last-moment) were obtained to determine C-reactive protein concentration, total leukocytes, platelets, erythrocytes, total plasma protein, serum albumin, urea, creatinine, and phosphorus. C-reactive protPloS onee0274510https://www.ebi.ac.uk/biostudies/studies/S-EPMC9499245biostudies-literatureC-reactive protein concentrations are higher in dogs with stage IV chronic kidney disease treated with intermittent hemodialysis.PMC9499245Poloni Batista BRodrigues Maia SFerreira de Souza FMogollon Garcia HDSalgueiro Geraldes SPinheiro Ferreira JCPicelli de Azevedo MGChalfun Guimaraes-Okamoto PTBilbau Sant'Anna PMelchert ASilveira de Moraes RMoreira Dos Santos Schmidt ERezende Dadalto CfalseC-reactive protein concentrations are higher in dogs with stage IV chronic kidney disease treated with intermittent hemodialysis.In chronic kidney disease dogs, the inflammatory process increases C-reactive protein concentrations. This study aimed to determine C-reactive protein serum concentrations in stage IV chronic kidney disease dogs treated with intermittent hemodialysis. A prospective cohort study was conducted with 23 dogs allocated into three groups: control group (CG, n = 7), intermittent hemodialysis group (IHG, n = 8) and clinical treatment group (CTG, n = 8), both comprised of stage IV chronic kidney disease dogs. One blood sample from CG (initial evaluation) and two samples from IHG and CTG (first- and last-moment) were obtained to determine C-reactive protein concentration, total leukocytes, platelets, erythrocytes, total plasma protein, serum albumin, urea, creatinine, and phosphorus. C-reactive prot2022-01-01T00:00:00Z20222025-04-18T20:53:51.937Z2025-04-07T08:58:43.812ZS-EPMC94992453613712910.1371/journal.pone.0274510