biostudies-literatureUnknown51(6)Smith BB<h4>Background</h4>Surgical site infections (SSIs) are an undesired perioperative outcome. Recent studies have shown increases in hospital acquired infections during the coronavirus disease 2019 (COVID-19) pandemic. The objective of this study was to evaluate postoperative SSIs in the COVID-19-era compared to a historical cohort at a large, multicenter, academic institution.<h4>Methods</h4>A retrospective review of all patients who underwent National Health and Safety Network (NHSN) inpatient surgical procedures between January 1, 2018 and December 31, 2020. Patients from the COVID-19-era (March-December 2020) were compared and matched 1:1 with historical controls (2018/2019) utilizing the standardized infection ratio (SIR) to detect difference.<h4>Results/discussion</h4>During the study pAmerican journal of infection control607-611https://www.ebi.ac.uk/biostudies/studies/S-EPMC9500048biostudies-literatureSurgical site infections during the COVID-19 era: A retrospective, multicenter analysis.PMC9500048Girardo MESmith BBBolton PBBosch WMurray AWMartin DPSingbartl KO'Horo JCHirte ILfalseSurgical site infections during the COVID-19 era: A retrospective, multicenter analysis.<h4>Background</h4>Surgical site infections (SSIs) are an undesired perioperative outcome. Recent studies have shown increases in hospital acquired infections during the coronavirus disease 2019 (COVID-19) pandemic. The objective of this study was to evaluate postoperative SSIs in the COVID-19-era compared to a historical cohort at a large, multicenter, academic institution.<h4>Methods</h4>A retrospective review of all patients who underwent National Health and Safety Network (NHSN) inpatient surgical procedures between January 1, 2018 and December 31, 2020. Patients from the COVID-19-era (March-December 2020) were compared and matched 1:1 with historical controls (2018/2019) utilizing the standardized infection ratio (SIR) to detect difference.<h4>Results/discussion</h4>During the study p2023-01-01T00:00:00Z2023 Jun2025-04-03T21:30:55.255Z2025-04-03T21:30:55.255ZS-EPMC95000483616260510.1016/j.ajic.2022.09.022