biostudies-literatureUnknown10Tiruneh C<h4>Objective</h4>To systematically summarize the burden of gastroschisis and omphalocele in Sub-Saharan Africa.<h4>Methods</h4>Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, systematically reviewed and meta-analyzed literatures from Medline (PubMed), Cochrane Library, HINARI, and Google Scholar that investigated at the prevalence of major congenital abdominal wall malformation. The pooled prevalence of major abdominal wall defects was estimated using a weighted inverse variance random-effects model. The Q statistic and the I² statistics were used to examine for heterogeneity among the included studies. The funnel plot and Egger's regression test were used to check for publication bias.<h4>Results</h4>A total of 1951 studies were identifSAGE open medicine20503121221125536https://www.ebi.ac.uk/biostudies/studies/S-EPMC9500260biostudies-literatureBirth prevalence of omphalocele and gastroschisis in Sub-Saharan Africa: A systematic review and meta-analysis.PMC9500260Gebremeskel TNecho MTeshome YTiruneh CTeshome DBelete AfalseBirth prevalence of omphalocele and gastroschisis in Sub-Saharan Africa: A systematic review and meta-analysis.<h4>Objective</h4>To systematically summarize the burden of gastroschisis and omphalocele in Sub-Saharan Africa.<h4>Methods</h4>Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, systematically reviewed and meta-analyzed literatures from Medline (PubMed), Cochrane Library, HINARI, and Google Scholar that investigated at the prevalence of major congenital abdominal wall malformation. The pooled prevalence of major abdominal wall defects was estimated using a weighted inverse variance random-effects model. The Q statistic and the I² statistics were used to examine for heterogeneity among the included studies. The funnel plot and Egger's regression test were used to check for publication bias.<h4>Results</h4>A total of 1951 studies were identif2022-01-01T00:00:00Z20222025-04-18T20:52:20.846Z2025-04-07T08:52:56.934ZS-EPMC95002603616121110.1177/20503121221125536