{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(9)"],"submitter":["Ahmed N"],"pubmed_abstract":["Aflatoxin B<sub>1</sub> (AF) is an unavoidable environmental pollutant that contaminates food, feed, and grains, which seriously threatens human and animal health. Arabic gum (AG) has recently evoked much attention owing to its promising therapeutic potential. Thus, the current study was conducted to look into the possible mechanisms beyond the ameliorative activity of AG against AF-inflicted hepatic injury. Male Wistar rats were assigned into four groups: Control, AG (7.5 g/kg b.w/day, orally), AF (200 µg/kg b.w), and AG plus AF group. AF induced marked liver damage expounded by considerable changes in biochemical profile and histological architecture. The oxidative stress stimulated by AF boosted the production of plasma malondialdehyde (MDA) level along with decreases in the total antio"],"journal":["Toxins"],"pagination":["605"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9500620"],"repository":["biostudies-literature"],"pubmed_title":["Arabic Gum Could Alleviate the Aflatoxin B<sub>1</sub>-provoked Hepatic Injury in Rat: The Involvement of Oxidative Stress, Inflammatory, and Apoptotic Pathways."],"pmcid":["PMC9500620"],"pubmed_authors":["Maher ZM","Ghamry HI","Khalil WF","El-Rayes SM","Youssef M","Ahmed N","Emam HT","Abdelkader A","Abdelrahaman D","Alsieni M","Ibrahim SF","Shanab O","Elserafy OS","Abdeen A","Ibrahim AN","Abdelrahman SM"],"additional_accession":[]},"is_claimable":false,"name":"Arabic Gum Could Alleviate the Aflatoxin B<sub>1</sub>-provoked Hepatic Injury in Rat: The Involvement of Oxidative Stress, Inflammatory, and Apoptotic Pathways.","description":"Aflatoxin B<sub>1</sub> (AF) is an unavoidable environmental pollutant that contaminates food, feed, and grains, which seriously threatens human and animal health. Arabic gum (AG) has recently evoked much attention owing to its promising therapeutic potential. Thus, the current study was conducted to look into the possible mechanisms beyond the ameliorative activity of AG against AF-inflicted hepatic injury. Male Wistar rats were assigned into four groups: Control, AG (7.5 g/kg b.w/day, orally), AF (200 µg/kg b.w), and AG plus AF group. AF induced marked liver damage expounded by considerable changes in biochemical profile and histological architecture. The oxidative stress stimulated by AF boosted the production of plasma malondialdehyde (MDA) level along with decreases in the total antio","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-22T00:36:25.541Z","creation":"2025-04-05T19:38:27.072Z"},"accession":"S-EPMC9500620","cross_references":{"pubmed":["36136543"],"doi":["10.3390/toxins14090605"]}}