{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yang J"],"funding":["Fok Ying Tong Education Foundation","MOE &amp; SAFEA for the 111 Project","National Natural Science Foundation of China"],"pagination":["3127"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9501013"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(18)"],"pubmed_abstract":["This paper reports a novel method to fabricate a bio-inspired SERS substrate with low reflectivity, ultra-sensitivity, excellent uniformity, and recyclability. First, double layers of polystyrene spheres with different particle sizes were assembled on the surface of a silicon wafer to act as a moth-like template. Second, through the template sacrifice method, the TiO<sub>2</sub> film with a three-dimensional moth-like eye structure was induced by the double-layer polystyrene spheres in the previous step, and its microscopic morphology showed a high degree of order. Finally, Ag nanoparticles were assembled on the TiO<sub>2</sub> film to form a bio-inspired SERS substrate. This ordered bio-inspired structure can not only reduce reflection, but also reinforce the uniformity of hotspot density, which helps to improve the sensitivity and uniformity of the Raman signal. This bio-inspired SERS substrate can detect R6G molecules at a concentration as low as 1.0 × 10<sup>-10</sup> mol/L, and its enhancement factor (EF) can reach 6.56 × 10<sup>6</sup>. In addition, the composite of Ag and TiO<sub>2</sub> can realize the photocatalytic degradation of R6G and then realize the recyclability of the SERS substrate."],"journal":["Nanomaterials (Basel, Switzerland)"],"pubmed_title":["A Novel Bio-Inspired Ag/3D-TiO<sub>2</sub>/Si SERS Substrate with Ordered Moth-like Structure."],"pmcid":["PMC9501013"],"funding_grant_id":["171039","B13025","21671081"],"pubmed_authors":["Yang J","Li Y","Petrescu FIT","Song D","Shi G"],"additional_accession":[]},"is_claimable":false,"name":"A Novel Bio-Inspired Ag/3D-TiO<sub>2</sub>/Si SERS Substrate with Ordered Moth-like Structure.","description":"This paper reports a novel method to fabricate a bio-inspired SERS substrate with low reflectivity, ultra-sensitivity, excellent uniformity, and recyclability. First, double layers of polystyrene spheres with different particle sizes were assembled on the surface of a silicon wafer to act as a moth-like template. Second, through the template sacrifice method, the TiO<sub>2</sub> film with a three-dimensional moth-like eye structure was induced by the double-layer polystyrene spheres in the previous step, and its microscopic morphology showed a high degree of order. Finally, Ag nanoparticles were assembled on the TiO<sub>2</sub> film to form a bio-inspired SERS substrate. This ordered bio-inspired structure can not only reduce reflection, but also reinforce the uniformity of hotspot density, which helps to improve the sensitivity and uniformity of the Raman signal. This bio-inspired SERS substrate can detect R6G molecules at a concentration as low as 1.0 × 10<sup>-10</sup> mol/L, and its enhancement factor (EF) can reach 6.56 × 10<sup>6</sup>. In addition, the composite of Ag and TiO<sub>2</sub> can realize the photocatalytic degradation of R6G and then realize the recyclability of the SERS substrate.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-19T07:29:27.373Z","creation":"2025-04-19T07:29:27.373Z"},"accession":"S-EPMC9501013","cross_references":{"pubmed":["36144914"],"doi":["10.3390/nano12183127"]}}