{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Jawad MU"],"funding":["NIH HHS"],"pagination":["5475"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9501210"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(18)"],"pubmed_abstract":["<h4>Background</h4>Cutaneous soft-tissue sarcoma (CSTS) of the head and neck are rare and are known to have aggressive clinical course. The current study utilizes a population-based registry in the U.S. to characterize these malignancies and explore disparities.<h4>Methods</h4>National Cancer Institute's (NCI) Surveillance, Epidemiology and End Result (SEER) database from 2000 to 2018 was queried to report incidence and survival data in 4253 cases in the U.S.<h4>Results</h4>Males were 5.37 times more likely and Non-Hispanic-White people (NHW) were 4.62 times more likely than females and Non-Hispanic-Black people (NHB) to develop CSTS of the head and neck. The overall incidence was 0.27 per 100,000 persons in 2018, with a significant increase since 2000. Advanced age and stage, histologic group other than 'fibromatous sarcoma' and lower SES groups were independent factors for worse overall survival.<h4>Conclusions</h4>CSTS of the head and neck demonstrate sex and racial/ethnic disparities in incidence and socioeconomic disparities in overall survival.<h4>Level of evidence</h4>II."],"journal":["Journal of clinical medicine"],"pubmed_title":["Head and Neck Cutaneous Soft-Tissue Sarcoma Demonstrate Sex and Racial/Ethnic Disparities in Incidence and Socioeconomic Disparities in Survival."],"pmcid":["PMC9501210"],"funding_grant_id":["#5K12-CA138464"],"pubmed_authors":["Zeitlinger LN","Randall RL","Traven SA","Monjazeb AM","Canter RJ","Bewley AF","Thorpe SW","O'Donnell EF","Carr-Ascher JR","Jawad MU"],"additional_accession":[]},"is_claimable":false,"name":"Head and Neck Cutaneous Soft-Tissue Sarcoma Demonstrate Sex and Racial/Ethnic Disparities in Incidence and Socioeconomic Disparities in Survival.","description":"<h4>Background</h4>Cutaneous soft-tissue sarcoma (CSTS) of the head and neck are rare and are known to have aggressive clinical course. The current study utilizes a population-based registry in the U.S. to characterize these malignancies and explore disparities.<h4>Methods</h4>National Cancer Institute's (NCI) Surveillance, Epidemiology and End Result (SEER) database from 2000 to 2018 was queried to report incidence and survival data in 4253 cases in the U.S.<h4>Results</h4>Males were 5.37 times more likely and Non-Hispanic-White people (NHW) were 4.62 times more likely than females and Non-Hispanic-Black people (NHB) to develop CSTS of the head and neck. The overall incidence was 0.27 per 100,000 persons in 2018, with a significant increase since 2000. Advanced age and stage, histologic group other than 'fibromatous sarcoma' and lower SES groups were independent factors for worse overall survival.<h4>Conclusions</h4>CSTS of the head and neck demonstrate sex and racial/ethnic disparities in incidence and socioeconomic disparities in overall survival.<h4>Level of evidence</h4>II.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-27T01:56:42.459Z","creation":"2025-04-06T18:24:17.007Z"},"accession":"S-EPMC9501210","cross_references":{"pubmed":["36143122"],"doi":["10.3390/jcm11185475"]}}