biostudies-literatureUnknown10Zhu C<h4>Background</h4>Acupuncture is increasingly used as adjuvant therapy for infertile women undergoing frozen-thawed embryo transfer (FET); however, its effects and safety are highly controversial. This study aimed to evaluate the pooled effects of adjuvant acupuncture on FET pregnancy outcomes.<h4>Methods</h4>We considered only randomized controlled trials (RCTs) that compared acupuncture with sham acupuncture or no adjuvant treatment during FET and the primary outcome was clinical pregnancy rate. Two authors separately selected studies, extracted data, and performed a risk of bias assessment. Pooled data were expressed as risk ratio (<i>RR</i>) or mean difference (<i>MD</i>), with a 95% confidence interval (<i>CI</i>). In addition, we conducted subgroup and sensitivity analyses to investFrontiers in public health987276https://www.ebi.ac.uk/biostudies/studies/S-EPMC9501879biostudies-literatureEffects of acupuncture on the pregnancy outcomes of frozen-thawed embryo transfer: A systematic review and meta-analysis.PMC9501879Zeng QHuang JZhang XLi FMa JXia WYu XZhu CfalseEffects of acupuncture on the pregnancy outcomes of frozen-thawed embryo transfer: A systematic review and meta-analysis.<h4>Background</h4>Acupuncture is increasingly used as adjuvant therapy for infertile women undergoing frozen-thawed embryo transfer (FET); however, its effects and safety are highly controversial. This study aimed to evaluate the pooled effects of adjuvant acupuncture on FET pregnancy outcomes.<h4>Methods</h4>We considered only randomized controlled trials (RCTs) that compared acupuncture with sham acupuncture or no adjuvant treatment during FET and the primary outcome was clinical pregnancy rate. Two authors separately selected studies, extracted data, and performed a risk of bias assessment. Pooled data were expressed as risk ratio (<i>RR</i>) or mean difference (<i>MD</i>), with a 95% confidence interval (<i>CI</i>). In addition, we conducted subgroup and sensitivity analyses to invest2022-01-01T00:00:00Z20222025-04-18T20:54:35.878Z2025-04-07T08:59:28.994ZS-EPMC95018793615923010.3389/fpubh.2022.987276