biostudies-literatureLeFaive JNHLBI NIH HHSNational Institutes of Health4248-4250https://www.ebi.ac.uk/biostudies/studies/S-EPMC9502232biostudies-literatureUnknown37(22)<h4>Summary</h4>The sparse allele vectors file format is an efficient storage format for large-scale DNA variation data and is designed for high throughput association analysis by leveraging techniques for fast deserialization of data into computer memory. A command line interface has been developed to complement the storage format and supports basic features like importing, exporting and subsetting. Additionally, a C++ programming API is available allowing for easy integration into analysis software.<h4>Availability and implementation</h4>https://github.com/statgen/savvy.<h4>Supplementary information</h4>Supplementary data are available at Bioinformatics online.Bioinformatics (Oxford, England)Sparse allele vectors and the savvy software suite.PMC9502232U01HL137182R01 HL1176263R01HL-117626-02S1U01 HL137182Kang HMAbecasis GSmith AVLeFaive JfalseSparse allele vectors and the savvy software suite.<h4>Summary</h4>The sparse allele vectors file format is an efficient storage format for large-scale DNA variation data and is designed for high throughput association analysis by leveraging techniques for fast deserialization of data into computer memory. A command line interface has been developed to complement the storage format and supports basic features like importing, exporting and subsetting. Additionally, a C++ programming API is available allowing for easy integration into analysis software.<h4>Availability and implementation</h4>https://github.com/statgen/savvy.<h4>Supplementary information</h4>Supplementary data are available at Bioinformatics online.2021-01-01T00:00:00Z2021 Nov2025-04-19T03:33:47.629Z2025-04-07T13:42:26.997ZS-EPMC95022323398938410.1093/bioinformatics/btab378