{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(9)"],"submitter":["De Meyer J"],"pubmed_abstract":["The use of saliva for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sparks debate due to presumed lower sensitivity and lack of standardization. Our aim was to evaluate the performance characteristics of (i) saliva collected by the ORAcollect<sup>TM</sup> device as a matrix for SARS-CoV-2 reverse-transcriptase polymerase chain reaction (RT-PCR), and (ii) 2 saliva rapid antigen tests (AgRDT). From 342 ambulatory individuals, both a nasopharyngeal swab and saliva sample via ORAcollect<sup>TM</sup> were obtained for a SARS-CoV-2 RT-PCR test. Furthermore, 54 and 123 additionally performed the V-Chek<sup>TM</sup> or Whistling<sup>TM</sup> saliva AgRDT. In total, 35% of individuals screened positive for SARS-CoV-2 via nasopharyngeal swab. Saliva, as a matrix for t"],"journal":["Viruses"],"pagination":["1931"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9502549"],"repository":["biostudies-literature"],"pubmed_title":["Evaluation of Saliva as a Matrix for RT-PCR Analysis and Two Rapid Antigen Tests for the Detection of SARS-CoV-2."],"pmcid":["PMC9502549"],"pubmed_authors":["De Meyer J","Goris H","Jansens H","Hans G","Goossens H","Mortele O","Vandamme S","Matheeussen V","Spiessens A"],"additional_accession":[]},"is_claimable":false,"name":"Evaluation of Saliva as a Matrix for RT-PCR Analysis and Two Rapid Antigen Tests for the Detection of SARS-CoV-2.","description":"The use of saliva for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sparks debate due to presumed lower sensitivity and lack of standardization. Our aim was to evaluate the performance characteristics of (i) saliva collected by the ORAcollect<sup>TM</sup> device as a matrix for SARS-CoV-2 reverse-transcriptase polymerase chain reaction (RT-PCR), and (ii) 2 saliva rapid antigen tests (AgRDT). From 342 ambulatory individuals, both a nasopharyngeal swab and saliva sample via ORAcollect<sup>TM</sup> were obtained for a SARS-CoV-2 RT-PCR test. Furthermore, 54 and 123 additionally performed the V-Chek<sup>TM</sup> or Whistling<sup>TM</sup> saliva AgRDT. In total, 35% of individuals screened positive for SARS-CoV-2 via nasopharyngeal swab. Saliva, as a matrix for t","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-27T02:02:53.573Z","creation":"2025-04-06T18:25:52.951Z"},"accession":"S-EPMC9502549","cross_references":{"pubmed":["36146737"],"doi":["10.3390/v14091931"]}}