biostudies-literatureNasrollahian SBabol University of Medical Sciences9520362https://www.ebi.ac.uk/biostudies/studies/S-EPMC9507725biostudies-literatureUnknown2022<h4>Background</h4>Infections due to carbapenem-resistant <i>Enterobacteriaceae</i> (CRE) are associated in patients with urinary catheters alarming rate of emergency status. The aim of this study is to investigate the molecular causes of carbapenem resistance among UPEC as well as antimicrobial resistance trends. Additionally, the potential of isolates to produce biofilms, in addition to their clonal and genetic diversity, was investigated. <i>Material and Methods</i>. A cross-sectional study was accomplished on a collection of 76 non-duplicate UPEC isolates obtained from CAUTIs from May 2021 to September 2021. The modified carbapenem inactivation method (mCIM) and EDTA-modified carbapenem inactivation method (eCIM) test was performed for the detection of carbapenemase and metallo-beta-laInternational journal of clinical practiceGenetic Diversity, Carbapenem Resistance Genes, and Biofilm Formation in UPEC Isolated from Patients with Catheter-Associated Urinary Tract Infection in North of Iran.PMC9507725724133549Rajabnia MPournajaf AArmaki MTNasrollahian SGholinia HHosseini ATeimourian MHalaji MfalseGenetic Diversity, Carbapenem Resistance Genes, and Biofilm Formation in UPEC Isolated from Patients with Catheter-Associated Urinary Tract Infection in North of Iran.<h4>Background</h4>Infections due to carbapenem-resistant <i>Enterobacteriaceae</i> (CRE) are associated in patients with urinary catheters alarming rate of emergency status. The aim of this study is to investigate the molecular causes of carbapenem resistance among UPEC as well as antimicrobial resistance trends. Additionally, the potential of isolates to produce biofilms, in addition to their clonal and genetic diversity, was investigated. <i>Material and Methods</i>. A cross-sectional study was accomplished on a collection of 76 non-duplicate UPEC isolates obtained from CAUTIs from May 2021 to September 2021. The modified carbapenem inactivation method (mCIM) and EDTA-modified carbapenem inactivation method (eCIM) test was performed for the detection of carbapenemase and metallo-beta-la2022-01-01T00:00:00Z20222025-05-18T13:42:33.541Z2025-05-18T13:42:33.541ZS-EPMC95077253618791110.1155/2022/9520362